NDLI: Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection

Content Provider	Springer Nature : BioMed Central
Author	Bogar, Lajos Molnar, Zsolt Tarsoly, Piroska Kenyeres, Peter Marton, Sandor
Abstract	Introduction Postoperative care after oesophageal tumour resection holds a high risk of respiratory complications. We therefore aimed to determine the value of systemic inflammatory markers in predicting arterial hypoxaemia as the earliest sign of developing lung injury after oesophageal tumour resection. Methods In a prospective observational study, 33 consecutive patients were observed for three days (T1–T3) after admission (T0) to an intensive care unit following oesophageal tumour resection. The daily highest values of the heart rate, axillary temperature, leukocyte count and PaCO2 were recorded. Serum C-reactive protein and procalcitonin concentrations and the leukocyte antisedimentation rate (LAR) were determined at T1 and T2. Respiratory function was monitored 6-hourly measurement of the PaO2/FIO2 ratio, and the lowest value was recorded at T3. Patients were categorised as normoxaemic or hypoxaemic using the cutoff value of 300 mmHg for PaO2/FIO2. Results Seventeen out of 33 patients were classified as hypoxaemic and 16 patients as normoxaemic at T3. Increases of temperature at T0 and of the procalcitonin and LAR values at T2 were predictive of hypoxaemia at T3 (P < 0.05, P < 0.01 and P < 0.001, respectively). The area under the receiver-operating characteristic curve was 0.65 for the temperature at T0, which was significantly lower than that for the procalcitonin level at T2 (0.83; 95% confidence interval, 0.69–0.97; P < 0.01) and that for LAR at T2 (0.89; 95% confidence interval, 0.77–1.00; P < 0.001). Conclusion These results suggest that an elevated LAR (>15%) and an elevated procalcitonin concentration (>2.5 ng/ml) measured on the second postoperative day can predict next-day arterial hypoxaemia (PaO2/FIO2 < 300 mmHg) after oesophageal tumour resection.
Related Links	https://ccforum.biomedcentral.com/counter/pdf/10.1186/cc4992.pdf
Ending Page	5
Page Count	5
Starting Page	1
File Format	HTM / HTML
ISSN	13648535
DOI	10.1186/cc4992
Journal	Critical Care
Issue Number	4
Volume Number	10
Language	English
Publisher	BioMed Central
Publisher Date	2006-07-19
Access Restriction	Open
Subject Keyword	Intensive Critical Care Medicine Emergency Medicine Procalcitonin Respiratory Insufficiency Axillary Temperature Multiple Organ Dysfunction Score Arterial Hypoxaemia
Content Type	Text
Resource Type	Article
Subject	Critical Care and Intensive Care Medicine
Journal Impact Factor	8.8/2023
5-Year Journal Impact Factor	10.4/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection

Decreases in procalcitonin and C-reactive protein are strong predictors of survival in ventilator-associated pneumonia

Sequential Organ Failure Assessment score and procalcitonin serum concentrations in patients with systolic heart failure early after cardiac surgery

Procalcitonin and C-reactive protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patients

Endotoxin adsorption method may affect serum procalcitonin

Procalcitonin serum levels in patients after liver, pancreas and simultaneous kidney-pancreas transplantations

Measurement of procalcitonin in bronchoalveolar lavage and serum as early predictors in acute respiratory distress syndrome

Increased procalcitonin serum levels as predictive parameter of multiple organ failure and outcome in acute pancreatitis patients

Multiple organ dysfunction syndrome: the scapegoat? Assessment of organ dysfunction between surviving and dying mice in the acute phase of polymicrobial sepsis

Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection

Similar Documents

Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection

Decreases in procalcitonin and C-reactive protein are strong predictors of survival in ventilator-associated pneumonia

Sequential Organ Failure Assessment score and procalcitonin serum concentrations in patients with systolic heart failure early after cardiac surgery

Procalcitonin and C-reactive protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patients

Endotoxin adsorption method may affect serum procalcitonin

Procalcitonin serum levels in patients after liver, pancreas and simultaneous kidney-pancreas transplantations

Measurement of procalcitonin in bronchoalveolar lavage and serum as early predictors in acute respiratory distress syndrome

Increased procalcitonin serum levels as predictive parameter of multiple organ failure and outcome in acute pancreatitis patients

Multiple organ dysfunction syndrome: the scapegoat? Assessment of organ dysfunction between surviving and dying mice in the acute phase of polymicrobial sepsis

Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection