NDLI: Measurement of PEEP-induced alveolar recruitment: just a research tool?

Content Provider	Springer Nature : BioMed Central
Author	De Michele, Michele Grasso, Salvatore
Abstract	For positive end-expiratory pressure (PEEP) to have lung protective efficacy in patients with acute respiratory distress syndrome, it must increase the end-expiratory lung volume through alveolar recruitment while avoiding lung over-inflation. PEEP may increase the end-expiratory lung volume either by increasing the proportion of aerated alveoli at end-expiration or by further inflating already ventilated lung regions. The optimal PEEP regimen is still a matter of debate. In theory, the ability to measure of PEEP-induced alveolar recruitment would be extremely useful in titrating PEEP at the bedside. However, until now this measurement has been confined to clinical research settings. Interesting work by Lu and coworkers, published in the previous issue of this journal, deals with the problem of measuring PEEP-induced alveolar recruitment. The 'gold standard' technique (i.e. the computed tomography method) is compared with the pressure-volume curve method. Because implementation of the latter method at the bedside would be relatively simple, that report, in addition to its intrinsic scientific value, may have important clinical implications.
Related Links	https://ccforum.biomedcentral.com/counter/pdf/10.1186/cc4974.pdf
Ending Page	2
Page Count	2
Starting Page	1
File Format	HTM / HTML
ISSN	13648535
DOI	10.1186/cc4974
Journal	Critical Care
Issue Number	4
Volume Number	10
Language	English
Publisher	BioMed Central
Publisher Date	2006-07-19
Access Restriction	Open
Subject Keyword	Intensive Critical Care Medicine Emergency Medicine Acute Respiratory Distress Syndrome Functional Residual Capacity Acute Respiratory Distress Syndrome Patient Peep Level High Peep
Content Type	Text
Subject	Critical Care and Intensive Care Medicine
Journal Impact Factor	8.8/2023
5-Year Journal Impact Factor	10.4/2023

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