NDLI: Locally relapsed and metastatic uterine leiomyoma: A case report

Content Provider	Springer Nature : BioMed Central
Author	Londero, Ambrogio P Perego, Patrizia Mangioni, Costantino Lellé, Ralph J Londero, Franco Marchesoni, Diego
Abstract	Introduction Benign metastasising leiomyoma refers to a type of lesion characterised by leiomyomatous alterations without any indication of malignancy. It presents as either a singular nodule or multiple nodules of proliferating smooth muscle cells and is generally found in the lungs of women who have undergone a hysterectomy. The purpose of this case report is to contribute to the knowledge of this rare disease by presenting evidence and experience of a patient case. In particular, this report seeks to investigate the therapeutic approaches in order to understand whether a standard of care can be prescribed and whether the use of prophylaxis therapy with progesterone as a follow-up to surgery serves as a reasonable treatment in certain cases diagnosed as benign metastasising leiomyoma. Case presentation We present the case of a 52-year-old Caucasian woman who developed a pelvic relapse and a pulmonary localisation of benign metastasising leiomyoma following a hysterectomy for myomatous uterus. Conclusion Our literature review revealed a single case of the use of chemoprophylaxis as treatment of a benign metastasising leiomyoma. The role of chemoprophylaxis in preventing future recurrences remains unclear. The use of progesterone as an adjuvant therapy for benign metastasising leiomyoma could simply be palliative, with associated psychological benefits, or it could be of therapeutic significance.
Related Links	https://jmedicalcasereports.biomedcentral.com/counter/pdf/10.1186/1752-1947-2-308.pdf
Ending Page	6
Page Count	6
Starting Page	1
File Format	HTM / HTML
ISSN	17521947
DOI	10.1186/1752-1947-2-308
Journal	Journal of Medical Case Reports
Issue Number	1
Volume Number	2
Language	English
Publisher	BioMed Central
Publisher Date	2008-09-23
Access Restriction	Open
Subject Keyword	Medicine Public Health General Practice Family Medicine Primary Care Medicine Surgical Oncology Internal Medicine Leiomyoma Goserelin Megestrol Specific Growth Factor Uterine Leiomyomas Medicine/Public Health
Content Type	Text
Resource Type	Case study
Subject	Medicine
Journal Impact Factor	0.9/2023

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