NDLI: The YvfTU Two-component System is involved in plcR expression in Bacillus cereus

Content Provider	Springer Nature : BioMed Central
Author	Brillard, Julien Susanna, Kim Michaud, Caroline Dargaignaratz, Claire Gohar, Michel Nielsen-Leroux, Christina Ramarao, Nalini Kolstø, Anne-Brit Nguyen-the, Christophe Lereclus, Didier Broussolle, Véronique
Abstract	Most extracellular virulence factors produced by Bacillus cereus are regulated by the pleiotropic transcriptional activator PlcR. Among strains belonging to the B. cereus group, the plcR gene is always located in the vicinity of genes encoding the YvfTU two-component system. The putative role of YvfTU in the expression of the PlcR regulon was therefore investigated. Expression of the plcR gene was monitored using a transcriptional fusion with a lacZ reporter gene in a yvfTU mutant and in its B. cereus ATCC 14579 parental strain. Two hours after the onset of the stationary phase, a stage at which the PlcR regulon is highly expressed, the plcR expression in the yvfTU mutant was only 50% of that of its parental strain. In addition to the reduced plcR expression in the yvfTU mutant, a few members of the PlcR regulon showed a differential expression, as revealed by transcriptomic and proteomic analyses. The virulence of the yvfTU mutant in a Galleria mellonella insect model was slightly lower than that of the parental strain. The YvfTU two-component system is not required for the expression of most of the virulence factors belonging to the PlcR regulon. However, YvfTU is involved in expression of plcR, a major regulator of virulence in B. cereus.
Related Links	https://bmcmicrobiol.biomedcentral.com/counter/pdf/10.1186/1471-2180-8-183.pdf
Ending Page	13
Page Count	13
Starting Page	1
File Format	HTM / HTML
ISSN	14712180
DOI	10.1186/1471-2180-8-183
Journal	BMC Microbiology
Issue Number	1
Volume Number	8
Language	English
Publisher	BioMed Central
Publisher Date	2008-10-16
Access Restriction	Open
Subject Keyword	Microbiology Biological Microscopy Mycology Parasitology Virology Life Sciences Histidine Kinase Strain ATCC Luria Broth Miller Unit Galleria Mellonella
Content Type	Text
Resource Type	Article
Subject	Microbiology Microbiology (medical)
Journal Impact Factor	4/2023
5-Year Journal Impact Factor	4.6/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The YvfTU Two-component System is involved in plcR expression in Bacillus cereus

Characterization of a small PlcR-regulated gene co-expressed with cereolysin O

A bacteria-specific 2[4Fe-4S] ferredoxin is essential in Pseudomonas aeruginosa

The Escherichia coli BarA-UvrY two-component system is a virulence determinant in the urinary tract

Response of Bacillus cereus ATCC 14579 to challenges with sublethal concentrations of enterocin AS-48

Bacillus cereus Fnr binds a [4Fe-4S] cluster and forms a ternary complex with ResD and PlcR

Antimicrobial and immunomodulatory responses of photodynamic therapy in Galleria mellonella model

Selective photoinactivation of Candida albicans in the non-vertebrate host infection model Galleria mellonella

Identification of two Mycobacterium tuberculosis H37Rv ORFs involved in resistance to killing by human macrophages

The YvfTU Two-component System is involved in plcR expression in Bacillus cereus

Similar Documents

The YvfTU Two-component System is involved in plcR expression in Bacillus cereus

Characterization of a small PlcR-regulated gene co-expressed with cereolysin O

A bacteria-specific 2[4Fe-4S] ferredoxin is essential in Pseudomonas aeruginosa

The Escherichia coli BarA-UvrY two-component system is a virulence determinant in the urinary tract

Response of Bacillus cereus ATCC 14579 to challenges with sublethal concentrations of enterocin AS-48

Bacillus cereus Fnr binds a [4Fe-4S] cluster and forms a ternary complex with ResD and PlcR

Antimicrobial and immunomodulatory responses of photodynamic therapy in Galleria mellonella model

Selective photoinactivation of Candida albicans in the non-vertebrate host infection model Galleria mellonella

Identification of two Mycobacterium tuberculosis H37Rv ORFs involved in resistance to killing by human macrophages

The YvfTU Two-component System is involved in plcR expression in Bacillus cereus