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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Bachelet-Rousseau, C. Kearney-Schwartz, A. Frimat, L. Kessler, M. Benetos, A. |
| Abstract | Increased arterial stiffness (AS) is a major determinant of cardiovascular complications in end-stage renal disease (ESRD) patients. Little is known about AS evolution after renal transplantation. The aim of the study was to characterize the evolution of AS after renal transplantation in a population of ESRD patients, in comparison to those patients remaining in dialysis. One hundred patients were recruited from the waiting list of the Transplant Unit of the University Hospital of Nancy. Two vascular evaluations were performed at one-year interval. AS was assessed by carotid/femoral pulse wave velocity (PWV). During this interval, thirtynine patients were transplanted and forty-nine remained on dialysis. At baseline PWV value was 10.6 ± 3.7 m/s. No difference was found between the two groups at the first and second visit. Mean arterial pressure (MAP) decreased in the transplant group (101 ± 14 vs. 95 ± 10 mmHg, p <0.01 respectively) at one-year follow up. Multivariate analysis showed that PWV changes depended on changes in MAP and baseline PWV. Although no difference in the one-year PWV evolution was found, the lower MAP value in the transplanted group could result in a better long term evolution of arterial stiffness in this group, leading to a better cardiovascular prognosis after renal transplantation. |
| Related Links | https://arteryresearch.biomedcentral.com/counter/pdf/10.1016/j.artres.2010.10.073.pdf |
| Ending Page | 166 |
| Page Count | 1 |
| Starting Page | 166 |
| File Format | HTM / HTML |
| ISSN | 18764401 |
| DOI | 10.1016/j.artres.2010.10.073 |
| Journal | Artery Research |
| Issue Number | 4 |
| Volume Number | 4 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2010-12-02 |
| Access Restriction | Open |
| Subject Keyword | Medicine Public Health Medicine/Public Health |
| Content Type | Text |
| Resource Type | Synopsis |
| Subject | Physiology (medical) Physiology |
| Journal Impact Factor | 0.9/2023 |
| 5-Year Journal Impact Factor | 0.7/2023 |
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