NDLI: Effect of soy phosphatidylserine supplemented diet on skin wrinkle and moisture in Vivo and clinical trial

Content Provider	Springer Nature Link
Author	Chung, Guk Hoon Yang, Ji Hee Kim, Yun Sook Choi, Hee Don Lee, Sang Hoon Han, Jeong Jun Hahm, Dae Hyun
Copyright Year	2013
Abstract	Effect of supplementation of phosphatidylserine (PS), enzymatically synthesized from soy lecithin, on skin moisture and wrinkle in animal and human was investigated. Skin moisture content of hairless mice was significantly decreased and skin thickness and wrinkle were significantly increased by UV irradiation, whereas PS-supplemented groups showed reduced wrinkle depth and much less wrinkle area unlike UV control (UV/Con) group. The collagen content in PS-supplemented groups increased compared with that in UV/Con group. A placebo-controlled double-blind intake study of soft capsules containing PS (300 mg/day) was performed on 63 subjects who had normal healthy skin for 12 weeks. Dermatologist’s visual assessment and image analysis of replicas showed that wrinkle near eye was improved by PSsupplementation. Upon measurement of moisture content in the skin, PS supplementation increased the moisture content in the skin. These findings showed that PS supplementation was effective in moisturizing and improving wrinkle of the skin in both animal and human; thus, PS could be used as an effective skin food ingredient.
Starting Page	227
Ending Page	235
Page Count	9
File Format	PDF
ISSN	17382203
Journal	Journal of the Korean Society for Applied Biological Chemistry
Volume Number	56
Issue Number	2
e-ISSN	2234344X
Language	English
Publisher	The Korean Society for Applied Biological Chemistry
Publisher Date	2013-04-30
Publisher Place	Seoul
Access Restriction	Subscribed
Subject Keyword	phosphatidylserine anti-wrinkle skin barrier function supplementation Applied Microbiology Biological Techniques moisturizing effect Bioorganic Chemistry
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry, Genetics and Molecular Biology

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