NDLI: Antioxidant and antitumor activities of β-glucan-rich exopolysaccharides with different molecular weight from Paenibacillus polymyxa JB115

Please wait, while we are loading the content...

Standardized Rhus verniciflua stokes extract and its major flavonoid fustin attenuate oxidative stress induced by tert-butyl hydroperoxide via activation of nuclear factor erythroid 2-related factor

Potential of 4′-(p-toluenesulfonylamide)-4-hydroxychalcone to inhibit the human cytochrome P450 2J2 isoform

Activation of C2H2-type zinc finger genes induces dwarfism in Arabidopsis thaliana

Antioxidant capacities and cytostatic effect of Korean red pepper (Capsicum annuum L): a screening and in vitro study

Kinetics and modeling of pepsin soluble collagen (PSC) extraction from the skin of malaysian catfish (Hybrid Clarias sp.)

High-throughput HDR inhibitor screening

Levels of biogenic amines in cheeses and their impact on biochemical and histological parameters in rats

Establishment of analytical method for 6-benzylaminopurine residue, a plant growth regulator for brown rice, mandarin, pepper, potato, and soybean by using GC/NPD

Purification of an iron-chelating peptide from spirulina protein hydrolysates

Differential protein expression profiling in Pleurotus ferulae mycelium caused by asafoetida extracts using a proteomics approach

Antioxidant and antitumor activities of β-glucan-rich exopolysaccharides with different molecular weight from Paenibacillus polymyxa JB115

The inhibitory effects of the ethanolic extract of Pimpinella brachycarpa on cytochrome P450 enzymes in humans

Intracellular uranium accumulation by Shewanella sp. HN-41 under the thiosulfate-reducing condition

Microbially facilitated incorporation of As(III) into bioreduced Fe-(hydr)oxide minerals

A novel methoxyflavonol derivative, 2-hydroxy-3-(2-methoxyphenyl)-1H-benzo[f]chromen-1-one (DK98), induces apoptosis in HCT116 human colon cancer cells

Determination of capsaicin, ascorbic acid, total phenolic compounds and antioxidant activity of Capsicum annuum L. var. serrano by mid infrared spectroscopy (Mid-FTIR) and chemometric analysis

Journal of the Korean Society for Applied Biological Chemistry : Volume 56

Journal of the Korean Society for Applied Biological Chemistry : Volume 55

Journal of the Korean Society for Applied Biological Chemistry : Volume 54

Journal of the Korean Society for Applied Biological Chemistry : Volume 53

Journal of the Korean Society for Applied Biological Chemistry : Volume 52

Antioxidant and antitumor activities of β-glucan-rich exopolysaccharides with different molecular weight from Paenibacillus polymyxa JB115

Content Provider	Springer Nature Link
Author	Hong, Joo Heon Jung, Hee Kyoung
Copyright Year	2014
Abstract	β-Glucan isolated from cell wall of fungi not only has low purity and yield, but also causes adverse effects. Consequently, extracellular β-glucan produced by microorganisms is the focus of this study. β-Glucan-rich exopolysaccharides (G-EPSs) with different molecular weights from Paenibacillus polymyxa JB115 were prepared by ultrafiltration and spray-drying. The weight-average molecular masses of the G-EPSs, P-SD-1 (spray-dried G-EPSs powder prepared below 100 kDa) and P-SD-2 (spray-dried G-EPSs powder prepared above 100 kDa), were 7.084×10$^{4}$ and 9.235×10$^{5}$ g/mol, respectively. β-Glucan content was 47.38% in P-SD-1 and 73.12% in P-SD-2. The hydroxyl radical- and superoxide radicalscavenging activities of P-SD-2 at 1 mg/mL (39.45 and 87.34%, respectively) were higher than those of P-SD-1 (30.32 and 53.06%, respectively). Maximal nitric oxide (22.24±1.34 μM) was generated in the presence of P-SD-2 (1 mg/mL) and the antitumor activity of P-SD-2 was higher than P-SD-1 in four tumor cell lines (HeLa, Sarcoma 180, A549, and Hep3B cells). Thus, antioxidant and antitumor activities could be enhanced by regulating the molecular weight of G-EPSs. We anticipate that the food and medicinal use of G-EPSs will follow further characterization of this class of exopolysaccharides.
Starting Page	105
Ending Page	112
Page Count	8
File Format	PDF
ISSN	17382203
Journal	Journal of the Korean Society for Applied Biological Chemistry
Volume Number	57
Issue Number	1
e-ISSN	2234344X
Language	English
Publisher	The Korean Society for Applied Biological Chemistry
Publisher Date	2014-02-28
Publisher Place	Seoul
Access Restriction	Subscribed
Subject Keyword	β-glucan Paenibacillus polymyxa antitumor activity Applied Microbiology exopolysaccharides Biological Techniques antioxidant activity Bioorganic Chemistry
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry, Genetics and Molecular Biology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Maturation of bone marrow-derived dendritic cells by a novel β-glucan purified from Paenibacillus polymyxa JB115.

Construction and expression of a novel Paenibacillus polymyxa GS01 bifunctional xyn43A-lin16A gene through overlap extension PCR

Isolation and purification of thermostable β-mannanase from Paenibacillus illinoisensis ZY-08

A novel beta-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages.

Physiological activities of a β-glucan produced by Panebacillus polymyxa

Isolation, purification and characterization of a thermostable β-mannanase from Paenibacillus sp. DZ3

Biochemical characterization of a noble xylanase from Paenibacillus sp. EC116

Antioxidant and antimicrobial activities of extracts from a medicinal plant, sea buckthorn

Antioxidant profile, antioxidant activity, and physicochemical characteristics of strawberries from different cultivars and harvest locations

Antioxidant and antitumor activities of β-glucan-rich exopolysaccharides with different molecular weight from Paenibacillus polymyxa JB115

Similar Documents

Maturation of bone marrow-derived dendritic cells by a novel β-glucan purified from Paenibacillus polymyxa JB115.

Construction and expression of a novel Paenibacillus polymyxa GS01 bifunctional xyn43A-lin16A gene through overlap extension PCR

Isolation and purification of thermostable β-mannanase from Paenibacillus illinoisensis ZY-08

A novel beta-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages.

Physiological activities of a β-glucan produced by Panebacillus polymyxa

Isolation, purification and characterization of a thermostable β-mannanase from Paenibacillus sp. DZ3

Biochemical characterization of a noble xylanase from Paenibacillus sp. EC116

Antioxidant and antimicrobial activities of extracts from a medicinal plant, sea buckthorn

Antioxidant profile, antioxidant activity, and physicochemical characteristics of strawberries from different cultivars and harvest locations

Antioxidant and antitumor activities of β-glucan-rich exopolysaccharides with different molecular weight from Paenibacillus polymyxa JB115