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  1. Toxicology and Environmental Health Sciences
  2. Toxicology and Environmental Health Sciences : Volume 4
  3. Toxicology and Environmental Health Sciences : Volume 4, Issue 2, June 2012
  4. Study on neurotoxicity of formaldehyde in mice
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Toxicology and Environmental Health Sciences : Volume 9
Toxicology and Environmental Health Sciences : Volume 8
Toxicology and Environmental Health Sciences : Volume 7
Toxicology and Environmental Health Sciences : Volume 6
Toxicology and Environmental Health Sciences : Volume 5
Toxicology and Environmental Health Sciences : Volume 4
Toxicology and Environmental Health Sciences : Volume 4, Issue 4, December 2012
Toxicology and Environmental Health Sciences : Volume 4, Issue 1, Supplement,October 2012
Toxicology and Environmental Health Sciences : Volume 4, Issue 3, September 2012
Toxicology and Environmental Health Sciences : Volume 4, Issue 2, June 2012
Preventive strategies aimed at reducing the health risks of Aflatoxin B$_{1}$
Identification of genes induced by dibutyl phthalate in human thyroid follicular FTC-238 cells
The association between lead concentration in the blood and neurobehavioral performance of children
A study on relationship between the participation in senior welfare programs and the recognition of health condition
The relationship between the change in digital infrared thermography imaging and preoperative and postoperative pain or disability in HNP patients
Effect of Cestrum diurnum and Casimiroa edulis plants on the digestive gland and its related enzymes in the freshwater snail Biomphalaria alexandrina
Study on neurotoxicity of formaldehyde in mice
Colloidal behaviors of ZnO nanoparticles in various aqueous media
Heterologous microarray hybridization used for differential gene expression profiling in Arochlor 1260-exposed marine medaka
Toxicology and Environmental Health Sciences : Volume 4, Issue 1, March 2012
Toxicology and Environmental Health Sciences : Volume 3
Toxicology and Environmental Health Sciences : Volume 2
Toxicology and Environmental Health Sciences : Volume 1

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Study on neurotoxicity of formaldehyde in mice

Content Provider Springer Nature Link
Author Dou, Xiao Ju Zhang, Yu Wu, Yu He
Copyright Year 2012
Abstract 48 Balb/C mice were exposed to different concentrations of gaseity formaldehyde. The neurotoxicity of formaldehyde was revealed at six aspects including step-down test, passive avoidance test, glial fibrillary acidic protein (GFAP) immunohistochemistry, activity of superoxide dismulase (SOD), content of malondialdehyde (MDA) and cell gel electrophoresis technology (SCGE). In step-down test and passive avoidance test, the mice exposed to formaldehyde at high dose and moderate dose has made notable errors, compared with control group (P<0.05). The GFAPpositive cells were increased with the increasing of doses. Activity of SOD and content of MDA were significant reduced after exposures at moderate dose and high dose (P<0.05). Formaldehyde can also induce to DNA tail length, tail moments and tail DNA changes with the increased dose. The data suggested the necessity for a systematic observance of precautions in case of occupational and dwellingrelated formaldehyde exposure.
Starting Page 115
Ending Page 120
Page Count 6
File Format PDF
ISSN 20059752
Journal Toxicology and Environmental Health Sciences
Volume Number 4
Issue Number 2
e-ISSN 22337784
Language English
Publisher Korean Society of Environmental Risk Assessment and Health Science
Publisher Date 2012-07-07
Publisher Place Springer
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Formaldehyde Memory disorders Behavioral response Neurotoxic mechanism Pharmacology/Toxicology Environmental Health
Content Type Text
Resource Type Article
Subject Health, Toxicology and Mutagenesis Toxicology
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