NDLI: First report of hepatitis E virus viremia in healthy blood donors from Nepal

Please wait, while we are loading the content...

Frequency of nucleotide sequence variations in the internal ribosome entry site region of hepatitis C virus RNA isolated from responding and non-responding patients with hepatitis C virus genotype 3 infection

Seroconversion and immunogenicity evaluation of seasonal influenza vaccine in mice model

Genotyping of human adenoviruses circulating in Southwest India

Characterization of genomic changes in the cervical pre-cancerous lesions and tumors induced by different types of human papillomaviruses

Agroinfection of tobacco by croton yellow vein mosaic virus and designing of a replicon vector for expression of foreign gene in plant

Indian porcine reproductive and respiratory syndrome virus bears discontinuous deletion of 30 amino acids in nonstructural protein 2

Serosurveillance of foot and mouth disease in Karnataka state, India: a 3 years study

Scientometric analysis of research on Zika virus

Molecular detection and characterization of a divergent isolate of Plantago asiatica mosaic virus in Plantago asiatica

First report of detection and molecular characterization of porcine parvovirus in domestic and wild pigs in Kerala, India

Isolation and characterization of genotype XIII Newcastle disease virus from Emu in India

A sensitive haemadsorption technique based RT-PCR for concentration and detection of Newcastle disease virus from clinical samples and allantoic fluid

First report of hepatitis E virus viremia in healthy blood donors from Nepal

First record of Pepper cryptic virus 2 in chilli (Capsicum annuum) in India

VirusDisease : Volume 27, Issue 2, June 2016

VirusDisease : Volume 27, Issue 1, March 2016

VirusDisease : Volume 26

VirusDisease : Volume 25

VirusDisease : Volume 24

VirusDisease : Volume 23

VirusDisease : Volume 22

VirusDisease : Volume 21

First report of hepatitis E virus viremia in healthy blood donors from Nepal

Content Provider	Springer Nature Link
Author	Gupta, Birendra Prasad Lama, Thupten K Adhikari, Anurag Shrestha, Ananta Rauniyar, Ramanuj Sapkota, Binay Thapa, Sandeep Shrestha, Smita Gupta, Pawan Prasad Manandhar, Krishna
Copyright Year	2016
Abstract	The aim of this study was to detect the prevalence of hepatitis E virus (HEV) in healthy blood donors so as to decipher the maintenance of (HEV) reservoir if any. Five hundred and eighty-one blood samples along with clinical information were collected from central blood bank, Kathmandu between February and March 2014. Samples were tested for hepatitis B virus surface antigen, anti-hepatitis C virus antibodies, anti-hepatitis A virus IgM, HEV antigen, HEV viral load and anti-HEV antibodies (IgM and IgG) by ELISA. Only those samples positive with anti-HEV IgM were tested for HEV RNA by reverse transcriptase nested PCR. Age adjusted prevalence of IgM anti HEV and IgG anti HEV were 3.6 and 8.3 % respectively. No significant difference in Median ALT levels was noted between HEV RNA positive and negative subjects. Sequence analysis of HEV shows all genotype belongs to genotype 1a. Phylogenetic analysis shows the virus has homology of 95 % with strain from India and Nepal outbreak of April 2014. This study sheds light on how inter epidemic reservoirs can be maintained in healthy population with asymptomatic cases. This raises an important question regarding nature of HEV as well as its tendency to circulate in blind sight and also cause periodic outbreaks in endemic setting like Kathmandu.
Starting Page	324
Ending Page	326
Page Count	3
File Format	PDF
ISSN	23473584
Journal	VirusDisease
Volume Number	27
Issue Number	3
e-ISSN	23473517
Language	English
Publisher	Springer India
Publisher Date	2016-08-10
Publisher Place	New Delhi
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	HEV Nepal Blood donors Microbiology Life Sciences Biochemistry Protein Structure Cell Biology
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Virology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

First report of hepatitis E virus viremia in healthy blood donors from Nepal.

Hepatitis E virus prevalence among blood donors in Dali, China

Deciphering the mystery of hepatitis B virus receptors: A historical perspective

Prevalence of hepatitis E virus in Chinese blood donors

In-silico design and molecular docking evaluation of peptides derivatives from bacteriocins and porcine beta defensin-2 as inhibitors of Hepatitis E virus capsid protein

Hepatitis E virus genotype 3 and capsid protein in the blood and urine of immunocompromised patients

Hepatitis E virus in hematopoietic stem cell donors: Towards a systematic HEV screening of donors?

Host proteins associated with Hepatitis C virus encoded NS4A

Unchanged high prevalence of antibodies to hepatitis E virus (HEV) and HEV RNA among blood donors with an elevated alanine aminotransferase level in Japan during 1991–2006

First report of hepatitis E virus viremia in healthy blood donors from Nepal

Similar Documents

First report of hepatitis E virus viremia in healthy blood donors from Nepal.

Hepatitis E virus prevalence among blood donors in Dali, China

Deciphering the mystery of hepatitis B virus receptors: A historical perspective

Prevalence of hepatitis E virus in Chinese blood donors

In-silico design and molecular docking evaluation of peptides derivatives from bacteriocins and porcine beta defensin-2 as inhibitors of Hepatitis E virus capsid protein

Hepatitis E virus genotype 3 and capsid protein in the blood and urine of immunocompromised patients

Hepatitis E virus in hematopoietic stem cell donors: Towards a systematic HEV screening of donors?

Host proteins associated with Hepatitis C virus encoded NS4A

Unchanged high prevalence of antibodies to hepatitis E virus (HEV) and HEV RNA among blood donors with an elevated alanine aminotransferase level in Japan during 1991–2006

First report of hepatitis E virus viremia in healthy blood donors from Nepal