NDLI: Effect of metabolic structures and energy requirements on curdlan production byAlcaligenes faecalis

Content Provider	Springer Nature Link
Author	Zheng, Zhi Yong Lee, Jin Woo Zhan, Xiao Bei Shi, Zhongping Wang, Lei Zhu, Li Wu, Jian Rong Lin, Chi Chung
Copyright Year	2007
Abstract	A comprehensive metabolic network was proposed forAlcaligenes faecalis and employed in a stoichiometrically based flux balance model for curdlan production optimization. The maximal yield of curdlan was evaluated for curdlan batch production. Various metabolic structures and metabolic pathway distributions related with the curdlan maximal yield was evaluated. The results showed that the energy efficiency rather than the substrate supply was the major constraint for the enhancement of curdlan production. The increase in specific rate of glucose uptake could enhance curdlan production yield due to the decrease of the ratio of metabolic maintenance to substrate consumption. However, some of the energy loss and nutrient limitation associated with the increase of metabolic maintenance would adversely affect the conversion efficiency of the substrate.
Starting Page	359
Ending Page	365
Page Count	7
File Format	PDF
ISSN	12268372
Journal	Biotechnology and Bioprocess Engineering
Volume Number	12
Issue Number	4
Language	English
Publisher	The Korean Society for Biotechnology and Bioengineering
Publisher Date	2007-01-01
Publisher Place	Seoul
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Alcaligenes faecalis bioenergetics curdlan metabolic flux analysis Biotechnology Industrial and Production Engineering
Content Type	Text
Resource Type	Article
Subject	Bioengineering Biomedical Engineering Applied Microbiology and Biotechnology Biotechnology

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