NDLI: Extraneural metastasizing ependymoma of the spinal cord

Content Provider	Springer Nature Link
Author	Graf, Matthias Blaeker, Hendrik Otto, Herwart F
Copyright Year	1999
Abstract	This paper reports a case of the rare entity of an extraneural metastasizing ependymoma of the spinal cord. The tumor which arose in the conus medullaris and in the cauda equina was first diagnosed in 1956 when a thoracolumbar myeloresection was performed. At autopsy, 40 years after the primary diagnosis, a massive local tumor recurrence with extraneural metastases in the lungs, the pleura, the liver, and the thoracal and abdominal lymph nodes were found. Immunohistochemical stains of the extraneural metastases showed a strong cytoplasmatic expression of glial fibrillary acidic protein (GFAP). Neither the primary tumor nor its metastases showed any of the conventional morphological criteria of malignancy. Reviewing the literature we discuss the possible mechanism of extraneural tumor spread and the incidence of metastases with regard to the tumor type.
Starting Page	56
Ending Page	60
Page Count	5
File Format	PDF
ISSN	12194956
Journal	Pathology & Oncology Research
Volume Number	5
Issue Number	1
Language	English
Publisher	Springer Netherlands
Publisher Date	1999-01-01
Publisher Place	Dordrecht
Access Restriction	Subscribed
Subject Keyword	extraneural metastases intraspinal tumor ependymoma Cancer Research Oncology Pathology Immunology Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Cancer Research Pathology and Forensic Medicine Oncology

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Extraneural metastasizing ependymoma of the spinal cord