NDLI: Food Omics Validation: Towards Understanding Key Features for Gut Microbiota, Probiotics and Human Health

Content Provider	Springer Nature Link
Author	Jiménez Pranteda, María Luján Pérez Davó, Azahara Monteoliva Sánchez, Mercedes Ramos Cormenzana, Alberto Aguilera, Margarita
Copyright Year	2014
Abstract	Probiotics are constituents of functional foods, which when administered in appropriate amounts confer a benefit to the host. Research studies performed on probiotics and gut microbiota along recent years have been focused on investigating the correlation between their molecular features and their impacts on individual health status. Consequently, many present and future challenges are being raised to elucidate the molecular bases of their interaction-mediated systemic effects, along with the ability to manipulate them for preventive and therapeutic interventions. Moreover, insights derived from the parallel evolution of “omics” technologies, with applications in different fields of biomedicine, are being efficiently transferred to this area of molecular microbiology. Thus, the present work compiles a summary of the general and useful omics applications: genomics, metagenomics, transcriptomics, proteomics, metabolomics, phenomics, and recently, integromics and interactomics and their putative use for validating models of interactions of the better-known probiotic microorganisms administered Lactobacillus and Bifidobacterium species. The impact on molecular resistance features, formula preparation, and route administration are also discussed. Omics tools will generate large amounts of data that, once correctly interpreted, are expected to rapidly validate the knowledge of probiotic molecular fundaments that trigger important positive human biological processes.
Starting Page	272
Ending Page	289
Page Count	18
File Format	PDF
ISSN	19369751
Journal	Food Analytical Methods
Volume Number	8
Issue Number	2
e-ISSN	1936976X
Language	English
Publisher	Springer US
Publisher Date	2014-08-06
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Probiotic Genomics Transcriptomics Proteomics Metabolomics Integromics Food Science Chemistry/Food Science Microbiology Analytical Chemistry
Content Type	Text
Resource Type	Article
Subject	Analytical Chemistry Safety Research Safety, Risk, Reliability and Quality Applied Microbiology and Biotechnology Food Science

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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