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| Content Provider | Springer Nature Link |
|---|---|
| Author | Edward Gnana Jothi, G. Kamatchi, S. Dhathathreyan, A. |
| Copyright Year | 2010 |
| Abstract | The adsorption of lipid Dioleoylphosphatidylcholine (DOPC) vesicles on a hydrophobic substrate has been investigated in aqueous buffer solution by means of the quartz crystal microbalance (QCM) and reflectometry. DOPC vesicles were prepared by the injection method on a hydrophobic substrate using 1-octadecanethiol (ODT) self-assembled on a gold-coated AT-cut quartz. The reflection spectrometry measurements of the adsorbed vesicles showed nearly monolayer formation in few cases, while in most other experiments, the frequency changes measured suggested multilayer formation assuming the usual Sauerbrey equation to hold in the present system as well. Presence of NaCl, KCl, Na$_{2}$SO$_{4}$ and ethanol in the aqueous phase during the formation of vesicles suggest that the multilayer formation can be hastened in some cases. Atomic force microscopic study corroborate the thicknesses that range between 8 and 20 nm for high concentration of electrolytes or ethanol suggesting coalescence of vesicles leading to several bilayers possibly stacked over each other. |
| Starting Page | 341 |
| Ending Page | 348 |
| Page Count | 8 |
| File Format | |
| ISSN | 09743626 |
| Journal | Journal of Chemical Sciences |
| Volume Number | 122 |
| Issue Number | 3 |
| e-ISSN | 09737103 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2010-08-11 |
| Publisher Institution | Indian Academy of Sciences |
| Publisher Place | India |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | DOPC vesicles supported multi-bilayers adsorption rupture QCM electrolytes Chemistry/Food Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry |
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