NDLI: The Analysis on Risk Factors and Clinical Treatment of Craniocerebral Injury Concurrent with Acute Kidney Injury

Content Provider	Springer Nature Link
Author	Cao, Yunxing Qiu, Jianwu Wang, Bing Xi, Huanjiu
Copyright Year	2014
Abstract	The main objective of this study was to investigate the risk factors and clinical treatment of craniocerebral injury concurrent with acute kidney injury. A total of 220 patients who suffered from craniocerebral injury from March 2010 to March 2012 in our Hospital were prospectively analyzed. Craniocerebral injury was defined according to the medical history, the verification of CT, and some investigated scores. The acute kidney injury was defined as a relative 47 % increase of serum creatinine. The method of multivariate logistic regression analysis was used to evaluate the possible risk factors associated with post-craniocerebral injury concurrent with acute kidney injury. The clinical treatments of craniocerebral injury concurrent with acute kidney injury were also identified via experimental results, and the pathological mechanism of craniocerebral injury concurrent with acute kidney injury was found to be related to cerebral tissue lesions, but some potential factors were ambiguous. The incidence of acute kidney injury was 70.2 % with craniocerebral injury. In hospital, mortality of acute kidney injury patients was 31.2 %, which was 6.019 times of non-acute kidney injury patients (p < 0.01). The incidence of acute kidney injury in patients with craniocerebral injury was 58.3 %, which was significantly higher compared to moderate and mild groups (p < 0.01). Unconditional multivariate logistic regression analysis results revealed that lower score, elderly, and male were the independent predictors of acute kidney injury episodes. Finally, some important factors were worthy of detailed study and further investigation.
Starting Page	199
Ending Page	204
Page Count	6
File Format	PDF
ISSN	10859195
Journal	Cell Biochemistry and Biophysics
Volume Number	71
Issue Number	1
e-ISSN	15590283
Language	English
Publisher	Springer US
Publisher Date	2014-11-15
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Craniocerebral injury Acute kidney injury Cerebral tissue lesions Ambiguous Mortality Logistic regression analysis Biochemistry Pharmacology/Toxicology Biotechnology Cell Biology Biophysics and Biological Physics
Content Type	Text
Resource Type	Article
Subject	Cell Biology Medicine Biochemistry Biophysics

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