NDLI: QT Dispersion and Prognostication of the Outcome in Acute Cardiotoxicities: A Comparison with SAPS II and APACHE II Scoring Systems

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QT Dispersion and Prognostication of the Outcome in Acute Cardiotoxicities: A Comparison with SAPS II and APACHE II Scoring Systems

Content Provider	Springer Nature Link
Author	Hassanian Moghaddam, Hossein Amiri, Hassan Zamani, Nasim Rahimi, Mitra Shadnia, Shahin Taherkhani, Maryam
Copyright Year	2013
Abstract	We aimed to evaluate the efficacy of QT dispersion (QTD) in determining the outcome of the patients poisoned by cardiotoxic medications and toxins. Patients who referred to our emergency department (ED) due to acute toxicity with any cardiotoxic medication or toxin and were admitted to medical toxicology intensive care unit (MTICU) were enrolled into the study. A questionnaire containing the demographic characteristics, vital signs, laboratory tests, electrocardiographic (ECG) parameters of the first ECG taken on MTICU or ED admission, simplified acute physiology score (SAPS), and acute physiology and chronic health evaluation (APACHE) score was filled for every single patient. QTD was manually calculated. The patients were divided into two groups of survivors and non-survivors and compared. Although QTD was not significantly different between the survivors and non-survivors (P = 0.8), SAPS II and APACHE II score were so. SAPS and APACHE had the highest sensitivity and specificity in determining the patients’ mortality, respectively. SAPS had the highest sensitivity, and QTD had the highest specificity in predicting the later development of the complications. SAPS II and APACHE II scoring systems are the best systems for prognostication of death in patients with acute cardiotoxic medication-induced poisonings. QTD can be successfully used for the prediction of complications.
Starting Page	129
Ending Page	133
Page Count	5
File Format	PDF
ISSN	15307905
Journal	Cardiovascular Toxicology
Volume Number	14
Issue Number	2
e-ISSN	15590259
Language	English
Publisher	Springer US
Publisher Date	2013-12-03
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	SAPS II APACHE II QT dispersion Poisoning Outcome Prognosis Complications Pharmacology/Toxicology Cardiology
Content Type	Text
Resource Type	Article
Subject	Molecular Biology Toxicology Cardiology and Cardiovascular Medicine

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