NDLI: Nitric oxide, caveolae, and vascular pathology

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Nitric oxide, caveolae, and vascular pathology

Content Provider	Springer Nature Link
Author	Li, Xiang An Everson, William Smart, Eric J.
Copyright Year	2006
Abstract	Endothelial nitric oxide synthase (eNOS) is an enzyme that plays a critical role in normal cardiovascular function. Caveolae are structures within the surface membrane of cells in which many signaling and second messenger pathways, including nitric oxide, are regulated. Many interventions in cardiovascular disease act, in part, either by changing factors that directly influence eNOS, or by changing a complex set of proteins that act indirectly on caveolae, to alter eNOS activity. In this review, we will focus on the regulation of eNOS activity by circulating factors which are altered in cardiovascular disease and the effects of pharmacological interventions that act partially through effects on eNOS.
Starting Page	1
Ending Page	13
Page Count	13
File Format	PDF
ISSN	15307905
Journal	Cardiovascular Toxicology
Volume Number	6
Issue Number	1
e-ISSN	15590259
Language	English
Publisher	Humana Press
Publisher Date	2006-01-01
Publisher Place	Totowa
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Pharmacology/Toxicology Cardiology
Content Type	Text
Resource Type	Article
Subject	Molecular Biology Toxicology Cardiology and Cardiovascular Medicine

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