NDLI: Biomineralization of a Self-assembled, Soft-Matrix Precursor: Enamel

Content Provider	Springer Nature Link
Author	Snead, Malcolm L.
Copyright Year	2015
Abstract	Enamel is the bioceramic covering of teeth, a composite tissue composed of hierarchical organized hydroxyapatite crystallites fabricated by cells under physiologic pH and temperature. Enamel material properties resist wear and fracture to serve a lifetime of chewing. Understanding the cellular and molecular mechanisms for enamel formation may allow a biology-inspired approach to material fabrication based on self-assembling proteins that control form and function. A genetic understanding of human diseases exposes insight from nature’s errors by exposing critical fabrication events that can be validated experimentally and duplicated in mice using genetic engineering to phenocopy the human disease so that it can be explored in detail. This approach led to an assessment of amelogenin protein self-assembly that, when altered, disrupts fabrication of the soft enamel protein matrix. A misassembled protein matrix precursor results in loss of cell-to-matrix contacts essential to fabrication and mineralization.
Starting Page	788
Ending Page	795
Page Count	8
File Format	PDF
ISSN	10474838
Journal	JOM
Volume Number	67
Issue Number	4
e-ISSN	15431851
Language	English
Publisher	Springer US
Publisher Date	2015-03-07
Publisher Institution	The Minerals, Metals & Materials Society (TMS)
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Engineering Chemistry/Food Science Physics Environment Earth Sciences
Content Type	Text
Resource Type	Article
Subject	Engineering Materials Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Biomineralization of a self-assembled-, soft-matrix precursor: Enamel

Self-Healing Metals and Metal Matrix Composites

Functional Metal Matrix Composites: Self-lubricating, Self-healing, and Nanocomposites-An Outlook

Fracture processes and mechanisms of crack growth resistance in human enamel

Applications of Polymer Matrix Syntactic Foams

Metal and Polymer Matrix Composites II

Manipulation and Characterization of a Novel Titanium Powder Precursor for Additive Manufacturing Applications

Development of a Precipitation-Strengthened Matrix for Non-quenchable Aluminum Metal Matrix Composites

Soft Magnetic Materials in High-Frequency, High-Power Conversion Applications

Biomineralization of a Self-assembled, Soft-Matrix Precursor: Enamel

Similar Documents

Biomineralization of a self-assembled-, soft-matrix precursor: Enamel

Self-Healing Metals and Metal Matrix Composites

Functional Metal Matrix Composites: Self-lubricating, Self-healing, and Nanocomposites-An Outlook

Fracture processes and mechanisms of crack growth resistance in human enamel

Applications of Polymer Matrix Syntactic Foams

Metal and Polymer Matrix Composites II

Manipulation and Characterization of a Novel Titanium Powder Precursor for Additive Manufacturing Applications

Development of a Precipitation-Strengthened Matrix for Non-quenchable Aluminum Metal Matrix Composites

Soft Magnetic Materials in High-Frequency, High-Power Conversion Applications

Biomineralization of a Self-assembled, Soft-Matrix Precursor: Enamel