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| Content Provider | Springer Nature Link |
|---|---|
| Author | Lim, Dong Hoon Choi, Dubok Kim, Sun Mi Piao, YuLan Choi, On You Lim, Geum Sook Chang, Young Cheol Cho, Hoon |
| Copyright Year | 2017 |
| Abstract | The hypolipidemic and antioxidant effects of dietary supplementation with polysaccharide isolated from Salicornia bigelovii seed (SBS) were evaluated in hypercholesterolemic rats. Following administration of SBS polysaccharide at 200mg/kg BW/day (HPS group), total cholesterol (TC), and low density lipoprotein cholesterol (LDLC) levels were 32.45% and 58.09% lower than those in negative controls (NC) group, respectively. However, in the case of high density lipoprotein cholesterol (HDLC), it was 36.37% higher than that of NC group. The arteriosclerosis and cardiac risk indices were 64.23% and 50.53% lower than in the NC group. However, the HTR (HDLC/TC) value was higher 2.05-fold than that of the NC group. Hydroxy-3-methylglutaryl CoA reductase activity in HPS group was 55.1% lower than that of the NC group. Activities of alanine transferase, aspartate aminotransferase, and alkaline phosphatase in HPS group were 29.71%, 26.49%, and 32.24%, lower than that of the NC group. SOD, CAT, and GSH-Px activities in HPS group were 31.05%, 49.29%, and 54.62% higher than that of the NC group. These results indicate that SBS polysaccharide has both hypolipidemic and antioxidant effects and shows potential for ameliorating hypercholesterolemia. |
| Starting Page | 787 |
| Ending Page | 796 |
| Page Count | 10 |
| File Format | |
| ISSN | 02561115 |
| Journal | Korean Journal of Chemical Engineering |
| Volume Number | 34 |
| Issue Number | 3 |
| e-ISSN | 19757220 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2017-02-13 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Hypolipidemic Activity Antioxidant Activity Polysaccharide Salicornia bigelovii Seed Industrial Chemistry/Chemical Engineering Catalysis Materials Science Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Chemical Engineering |
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