NDLI: Biodegradable polycaprolactone/cuttlebone scaffold composite using salt leaching process

Content Provider	Springer Nature Link
Author	Park, Jong Seok Lim, Youn Mook Youn, Min Ho Gwon, Hui Jeong Nho, Young Chang
Copyright Year	2012
Abstract	We prepared biodegradable polycaprolactone/cuttlebone scaffold composite by salt leaching process. In the first step, a co-continuous blend of biodegradable materials, polycaprolactone (PCL) and cuttlebone (CB), and an amount of sodium chloride salt particles were mixed using a stirrer. Next, the extraction of mineral salts using de-ionized distilled water was performed using a biodegradable PCL/CB scaffold with fully interconnected pores. Finally, the durable morphology of the scaffolds was fabricated by freeze-drying process at −53 °C for 24 hrs in a vacuum. In addition, the quadrilateral pres ranged from about 250 to 300 μm in diameter. Scanning electron microscopy (SEM) and mercury intrusion porosimeter techniques were carried out to characterize the pore morphology. By increasing the CB and sodium chloride salt particle content, the number of interconnected pores, material properties, and pore morphology were dramatically changed. The average compressive strengths (load at 50% strain) of the different porous PCL/CB scaffolds were found to decrease from 133 to about 79 (load at 50% strain, gf) with an increase in porosity. The values of the porosity increased as the sodium chloride salt volume fraction increased
Starting Page	931
Ending Page	934
Page Count	4
File Format	PDF
ISSN	02561115
Journal	Korean Journal of Chemical Engineering
Volume Number	29
Issue Number	7
e-ISSN	19757220
Language	English
Publisher	Springer US
Publisher Date	2012-02-02
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Polycaprolactone (PCL) Cuttlebone (CB) Scaffold Biocompatibility Industrial Chemistry/Chemical Engineering Catalysis Biotechnology Materials Science
Content Type	Text
Resource Type	Article
Subject	Chemistry Chemical Engineering

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