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  1. In Vitro Cellular & Developmental Biology - Animal
  2. In Vitro Cellular & Developmental Biology - Animal : Volume 43
  3. In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 10, December 2007
  4. Application of methods for viral clearance in stem cell production
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In Vitro Cellular & Developmental Biology - Animal : Volume 53
In Vitro Cellular & Developmental Biology - Animal : Volume 52
In Vitro Cellular & Developmental Biology - Animal : Volume 51
In Vitro Cellular & Developmental Biology - Animal : Volume 50
In Vitro Cellular & Developmental Biology - Animal : Volume 49
In Vitro Cellular & Developmental Biology - Animal : Volume 48
In Vitro Cellular & Developmental Biology - Animal : Volume 47
In Vitro Cellular & Developmental Biology - Animal : Volume 46
In Vitro Cellular & Developmental Biology - Animal : Volume 45
In Vitro Cellular & Developmental Biology - Animal : Volume 44
In Vitro Cellular & Developmental Biology - Animal : Volume 43
In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 10, December 2007
In memoriam: Leonard J. Schiff, Ph.D. (1938–2007)
Ceramide kinase expression is altered during macrophage-like cell differentiation of the leukemia cell line HL-60
Isolation, culture, and characterization of canine Sertoli cells
Formation and characterization of three dimensional human hepatocyte cell line spheroids on chitosan matrix for in vitro tissue engineering applications
Glycated type 1 collagen induces endothelial dysfunction in culture
Species identification in cell culture: a two-pronged molecular approach
Development of an AT$_{2}$-deficient proximal tubule cell line for transport studies
RPE-derived factors modulate photoreceptor differentiation: A possible role in the retinal stem cell niche
Application of methods for viral clearance in stem cell production
Cytotoxic effect of achatinin$_{H}$ (lectin) from Achatina fulica against a human mammary carcinoma cell line (MCF7)
In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 8-9, October 2007
In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 7, August 2007
In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 5-6, June 2007
In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 1, Supplement,May 2007
In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 3-4, April 2007
In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 2, February 2007
In Vitro Cellular & Developmental Biology - Animal : Volume 43, Issue 1, January 2007
In Vitro Cellular & Developmental Biology - Animal : Volume 42
In Vitro Cellular & Developmental Biology - Animal : Volume 41
In Vitro Cellular & Developmental Biology - Animal : Volume 40
In Vitro Cellular & Developmental Biology - Animal : Volume 39
In Vitro Cellular & Developmental Biology - Animal : Volume 38
In Vitro Cellular & Developmental Biology - Animal : Volume 37
In Vitro Cellular & Developmental Biology - Animal : Volume 36
In Vitro Cellular & Developmental Biology - Animal : Volume 35
In Vitro Cellular & Developmental Biology - Animal : Volume 34
In Vitro Cellular & Developmental Biology - Animal : Volume 33

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Application of methods for viral clearance in stem cell production

Content Provider Springer Nature Link
Author Cobo, Fernando
Copyright Year 2007
Abstract Regenerative medicine therapies will allow in the future the transplant of cells of human origin in some diseases that until now have been incurable. The assurance of the safety and quality, especially from a microbiological point of view, is very important for these therapeutic products. Depending on the starting material, there are several sources of pathogen presence, mainly human viruses. Also, the use of feeders of animal origin as layers in which the stem cells can grow may permit the transmission of animal pathogens to these cells. However, cell sources are limited due to the low availability of spare in vitro fecundation human embryos and the low rate of success in the derivation of human stem cell lines. Thus, in several cases, it will be necessary to evaluate the possibility of removing or inactivating these microorganisms. In this paper, we summarize the main methods of viral clearance and we have provided an overview of the main features taking into account in the viral clearance techniques.
Starting Page 371
Ending Page 378
Page Count 8
File Format PDF
ISSN 10712690
Journal In Vitro Cellular & Developmental Biology - Animal
Volume Number 43
Issue Number 10
e-ISSN 1543706X
Language English
Publisher Springer-Verlag
Publisher Date 2007-10-13
Publisher Place New York
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Viral clearance Stem cell lines Stem cell banks Cell therapy Animal Physiology Animal Biochemistry Animal Genetics and Genomics Developmental Biology Cell Biology
Content Type Text
Resource Type Article
Subject Cell Biology Developmental Biology Medicine
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