NDLI: Specimen-specific vertebral fracture modeling: a feasibility study using the extended finite element method

Content Provider	Springer Nature Link
Author	Giambini, Hugo Qin, Xiaoliang Dragomir Daescu, Dan An, Kai Nan Nassr, Ahmad
Copyright Year	2015
Abstract	Osteoporotic vertebral body fractures are an increasing clinical problem among the aging population. Specimen-specific finite element models, derived from quantitative computed tomography (QCT), have the potential to more accurately predict failure loads in the vertebra. Additionally, the use of extended finite element modeling (X-FEM) allows for a detailed analysis of crack initiation and propagation in various materials. Our aim was to study the feasibility of QCT/X-FEM analysis to predict fracture properties of vertebral bodies. Three cadaveric specimens were obtained, and the L3 vertebrae were excised. The vertebrae were CT scanned to develop computational models and mechanically tested in compression to measure failure load, stiffness and to observe crack location. One vertebra was used for calibration of the material properties from experimental results and CT gray-scale values. The two additional specimens were used to assess the model prediction. The resulting QCT/X-FEM model of the specimen used for calibration had 2 and 4 % errors in stiffness and failure load, respectively, compared with the experiment. The predicted failure loads of the additional two vertebrae were larger by about 41–44 % when compared to the measured values, while the stiffness differed by 129 and 40 %. The predicted fracture patterns matched fairly well with the visually observed experimental cracks. Our feasibility study indicated that the QCT/X-FEM method used to predict vertebral compression fractures is a promising tool to consider in future applications for improving vertebral fracture risk prediction in the elderly.
Starting Page	583
Ending Page	593
Page Count	11
File Format	PDF
ISSN	01400118
Journal	Medical and Biological Engineering and Computing
Volume Number	54
Issue Number	4
e-ISSN	17410444
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2015-08-04
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Vertebral fracture Extended finite element method Osteoporosis Aging Crack propagation Human Physiology Biomedical Engineering Imaging Radiology Computer Applications
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering Computer Science Applications

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Sensitivity of patient-specific vertebral finite element model from low dose imaging to material properties and loading conditions

A quasi-brittle continuum damage finite element model of the human proximal femur based on element deletion

Geometry reconstruction method for patient-specific finite element models for the assessment of tibia fracture risk in osteogenesis imperfecta

Method for patient-specific finite element modeling and simulation of deep brain stimulation

Influence of head mass on temporo-parietal skull impact using finite element modeling

Biomechanics of thoracolumbar junction vertebral fractures from various kinematic conditions

Finite element modeling of mitral leaflet tissue using a layered shell approximation

Buttressing angle of the double-plating fixation of a distal radius fracture: a finite element study

Inverse finite-element modeling for tissue parameter identification using a rolling indentation probe

Specimen-specific vertebral fracture modeling: a feasibility study using the extended finite element method

Similar Documents

Sensitivity of patient-specific vertebral finite element model from low dose imaging to material properties and loading conditions

A quasi-brittle continuum damage finite element model of the human proximal femur based on element deletion

Geometry reconstruction method for patient-specific finite element models for the assessment of tibia fracture risk in osteogenesis imperfecta

Method for patient-specific finite element modeling and simulation of deep brain stimulation

Influence of head mass on temporo-parietal skull impact using finite element modeling

Biomechanics of thoracolumbar junction vertebral fractures from various kinematic conditions

Finite element modeling of mitral leaflet tissue using a layered shell approximation

Buttressing angle of the double-plating fixation of a distal radius fracture: a finite element study

Inverse finite-element modeling for tissue parameter identification using a rolling indentation probe

Specimen-specific vertebral fracture modeling: a feasibility study using the extended finite element method