NDLI: NeuroAIDS, Drug Abuse, and Inflammation: Building Collaborative Research Activities

Content Provider	Springer Nature Link
Author	Berman, Joan W. Carson, Monica J. Chang, Linda Cox, Brian M. Fox, Howard S. Gonzalez, R. Gilberto Hanson, Glen R. Hauser, Kurt F. Ho, Wen Zhe Hong, Jau Shyong Major, Eugene O. Maragos, William F. Masliah, Eliezer McArthur, Justin C. Miller, Diane B. Nath, Avindra O’Callaghan, James P. Persidsky, Yuri Power, Christopher Rogers, Thomas J. Royal, Walter
Copyright Year	2006
Abstract	Neurological complications of human immunodeficiency virus (HIV) infection are a public health problem despite the availability of active antiretroviral therapies. The neuropathogenesis of HIV infection revolves around a complex cascade of events that include viral infection and glial immune activation, monocyte–macrophage brain infiltration, and secretion of a host of viral and cellular inflammatory and neurotoxic molecules. Although there is evidence that HIV-infected drug abusers experience more severe neurological disease, the biological basis for this finding is unknown. A scientific workshop organized by the National Institute on Drug Abuse (NIDA) was held on March 23–24, 2006 to address this question. The goal of the meeting was to bring together basic science and clinical researchers who are experts in NeuroAIDS, glial immunity, drugs of abuse, and/or pharmacology in order to find new approaches to understanding interactions between drug abuse and neuroAIDS. The format of the meeting was designed to stimulate open discussion and forge new multidisciplinary research collaborations. This report includes transcripts of active discussions and short presentations from invited participants. The presentations were separated into sections that included: Glial Biology, Inflammation, and HIV; Pharmacology, Neurotoxicology, and Neuroprotection; NeuroAIDS and Virology; and Virus–Drug and Immune–Drug Interactions. Research priorities were identified. Additional information about this meeting is available through links from the NIDA AIDS Research Program website ( http://www.nida.nih.gov/about/organization/arp/arp-websites.htm ).
Starting Page	351
Ending Page	399
Page Count	49
File Format	PDF
ISSN	15571890
Journal	Journal of Neuroimmune Pharmacology
Volume Number	1
Issue Number	4
e-ISSN	15571904
Language	English
Publisher	Kluwer Academic Publishers-Plenum Publishers
Publisher Date	2006-11-08
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	NeuroAIDS drug abuse HIV SIV inflammation brain Cell Biology Virology Pharmacology/Toxicology Immunology Neurosciences
Content Type	Text
Resource Type	Article
Subject	Neuroscience Immunology and Allergy Pharmacology Immunology

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