NDLI: Bioactivity and constituents of several common seaweeds

Content Provider	Springer Nature Link
Author	Zhang, Yi Han, JinYuan Mu, Jun Feng, Yan Gu, XiaoJie Ji, YuanXi
Copyright Year	2013
Abstract	Bioactivity and constituents of 8 common seaweeds from Dalian intertidal zone of northern Yellow Sea were investigated. In the anti-methicillin-resistant Staphylococcus aureus (MRSA) test, Symphyocladia latiuscula and Enteromorpha intestinalis showed obvious activities with MICs much lower than 1.0 mg mL$^{−1}$. In the DNA damage repair test (DDRT), Chondrus ocellatu showed selective inhibitory activity against the DNA repair-defective E. coli strain vs. the wild-type E. coli strain; while Sym. latiuscula, Enteromorpha intestinalis and Sar. kjellmanianum showed significant anti-E. coli activity with MICs of 64–128 μg mL$^{−1}$. In the anti-Pyricularia oryzae test, Sym. latiuscula and Rh. confervoides strongly inhibited the germination of the spores of P. oryzae on agar plate. In the brine shrimp larvicidal test, Sym. latiuscula, Rh. confervoides and Sar. kjellmanianum exhibited potent toxicity against brine shrimp larvae, with LC$_{50}$ much lower than 1 mg mL$^{−1}$. The HPTLC analysis revealed their diversified secondary metabolites. The HPLC-DAD-MS analysis of the strongest species Sym. latiuscula and database searching showed that it can produce quite diversified metabolites, including halogenated ones, some of which may be new natural products. The results demonstrated the potentials of these seaweeds in the development of new antibiotics, antitumor drugs, agricultural fungicides and pesticides.
Starting Page	2282
Ending Page	2289
Page Count	8
File Format	PDF
ISSN	10016538
Journal	Chinese Science Bulletin
Volume Number	58
Issue Number	19
e-ISSN	18619541
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2013-07-18
Publisher Place	Berlin, Heidelberg
Access Restriction	Subscribed
Subject Keyword	saweeds biomass antibacterial antifungal larvicidal HPTLC HPLC-DAD-MS Science Life Sciences Physics Chemistry/Food Science Earth Sciences Engineering
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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