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| Content Provider | Springer Nature Link |
|---|---|
| Author | Liu, Di Zhang, Xiang Bin Yan, Zhuan Qiang Chen, Feng Ji, Jun Qin, Jian Ping Li, Hai Yan Lu, Jun Peng Xue, Yu Liu, Jia Jia Xie, Qing Mei Ma, Jing Yun Xue, Chun Yi Bee, Ying Zuo |
| Copyright Year | 2012 |
| Abstract | Infectious bursal disease virus (IBDV) is a double-stranded RNA virus that causes immunosuppressive disease in young chickens. Thousands of cases of IBDV infection are reported each year in South China, and these infections can result in considerable economic losses to the poultry industry. To monitor variations of the virus during the outbreaks, 30 IBDVs were identified from vaccinated chicken flocks from nine provinces in South China in 2011. VP2 fragments from different virus strains were sequenced and analyzed by comparison with the published sequences of IBDV strains from China and around the world. Phylogenetic analysis of hypervariable regions of the VP2 (vVP2) gene showed that 29 of the isolates were very virulent (vv) IBDVs, and were closely related to vvIBDV strains from Europe and Asia. Alignment analysis of the deduced amino acid (aa) sequences of vVP2 showed the 29 vv isolates had high uniformity, indicated low variability and slow evolution of the virus. The non-vvIBDV isolate JX2-11 was associated with higher than expected mortality, and had high deduced aa sequence similarity (99.2 %) with the attenuated vaccine strain B87 (BJ). The present study has demonstrated the continued circulation of IBDV strains in South China, and emphasizes the importance of reinforcing IBDV surveillance. |
| Starting Page | 1107 |
| Ending Page | 1112 |
| Page Count | 6 |
| File Format | |
| ISSN | 00494747 |
| Journal | Tropical Animal Health and Production |
| Volume Number | 45 |
| Issue Number | 5 |
| e-ISSN | 15737438 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2012-12-02 |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Infectious bursal disease virus (IBDV) VP2 gene Molecular characterization Phylogenetic analysis South China Zoology Veterinary Medicine |
| Content Type | Text |
| Resource Type | Article |
| Subject | Animal Science and Zoology Food Animals |
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