NDLI: Heterogeneous organization of a tandem repeat family in subtelomeric heterochromatin of rye

Content Provider	Springer Nature Link
Author	Evtushenko, E. V. Vershinin, A. V.
Copyright Year	2010
Abstract	The presence of tandem repeat multicopy families in subtelomeric regions of all chromosomes is a characteristic feature of the rye karyotype, in contrast to the organization of these regions in chromosomes of extensively studied species, such as human, rice, and Arabidopsis. To study the molecular structure of these regions, we analyzed BAC clones from a library constructed from the genetic material of rye chromosome 1 short arm (1RS). Screening of the library detected numerous clones that contained copies of multicopy tandem families of DNA sequences pSc200, pSc250, and pSc119.2. An examination of the molecular organization of tandem arrays of the pSc200 family, which is the most common in the rye genome, showed that the subtelomeric 1RS region includes several such arrays, each of which contains characteristic blocks of multimers of various periodicity. Such pattern of heterogeneous organization of tandem repeat arrays differs from the view of the tandem arrays as monotonous sequence of identical monomers, which was generally accepted in recent past.
Starting Page	1074
Ending Page	1076
Page Count	3
File Format	PDF
ISSN	10227954
Journal	Russian Journal of Genetics
Volume Number	46
Issue Number	9
e-ISSN	16083369
Language	English
Publisher	SP MAIK Nauka/Interperiodica
Publisher Date	2010-09-30
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Microbial Genetics and Genomics Animal Genetics and Genomics Human Genetics
Content Type	Text
Resource Type	Article
Subject	Genetics

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