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| Content Provider | Springer Nature Link |
|---|---|
| Author | Enaganti, Srujan Kumar Ibarra, Oscar H. Kari, Lila Kopecki, Steffen |
| Copyright Year | 2016 |
| Abstract | This paper investigates properties of the binary string and language operation overlap assembly which was defined by Csuhaj-Varjú, Petre and Vaszil as a formal model of the linear self-assembly of DNA strands: The overlap assembly of two strings, xy and yz, which share an “overlap” y, results in the string xyz. The study of overlap assembly as a formal language operation is part of ongoing efforts to provide a formal framework and rigorous treatment of DNA-based information and DNA-based computation. Other studies along these lines include theoretical explorations of splicing systems, insertion/deletion systems, substitution, hairpin extension, hairpin reduction, superposition, overlapping catenation, conditional concatenation, contextual intra- and intermolecular recombinations, template guided recombination, as well as directed extension by PCR. In this context, we investigate overlap assembly and its properties: closure properties of basic language families under this operation, decision problems, as well as the possible use of iterated overlap assembly to generate combinatorial DNA libraries. |
| Starting Page | 175 |
| Ending Page | 185 |
| Page Count | 11 |
| File Format | |
| ISSN | 15677818 |
| Journal | Natural Computing |
| Volume Number | 16 |
| Issue Number | 1 |
| e-ISSN | 15729796 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2016-01-23 |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Formal language operations DNA computing Overlap assembly Combinatorial libraries Theory of Computation Evolutionary Biology Processor Architectures Artificial Intelligence (incl. Robotics) Complex Systems |
| Content Type | Text |
| Resource Type | Article |
| Subject | Computer Science Applications |
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