NDLI: Preparation and characterization of natural polymers as stabilizer for magnetic nanoparticles by gamma irradiation

Content Provider	Springer Nature Link
Author	Eid, M.
Copyright Year	2013
Abstract	Hydroxyethyl methacryate (HEMA)-Agar and Hydroxyethyl methacryate (HEMA)-Gelatin hydrogels have been prepared by gamma radiation as polymeric stabilizer for magnetic nanoparticles via radiation technique and loading co-precipitation technique. The swelling property of the prepared hydrogels in bidistilled water and different pH’s was studied and the results showed that, the swelling percent of the plain hydrogel was found to be higher for all different compositions. The morphology and structure of the prepared hydrogels and dispersion of the magnetic nanoparticles in the hydrogel network were examined by Scanning electron microscopy (SEM) and Infrared spectroscopy (FT-IR). The particle size of the formed magnetic nanoparticles has been confirmed by Dynamic light scattering (DLS) and Transmission electron microscope (TEM), and it was found to be smaller in loading co-precipitation technique than irradiation technique. The HEMA-Gelatin-Fe$_{3}$O$_{4}$ has higher particle size than HEMA-Agar-Fe$_{3}$O$_{4}$ (HAF). Finally, the drug loading capacities of the magnetic nanoparticles and their releasing dependence on different pH were investigated with doxorubicin hydrochloride (DOX) as an anticancer drug model.
Starting Page	1
Ending Page	11
Page Count	11
File Format	PDF
ISSN	10229760
Journal	Journal of Polymer Research
Volume Number	20
Issue Number	3
e-ISSN	15728935
Language	English
Publisher	Springer Netherlands
Publisher Date	2013-02-28
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	HEMA Natural polymers Fe$_{3}$O$_{4}$ nanoparticles DLS TEM Doxorubicin Polymer Sciences Industrial Chemistry/Chemical Engineering Characterization and Evaluation of Materials
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Materials Chemistry Polymers and Plastics

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