NDLI: Chemical Synthesis of Monodisperse Magnetic Nanoparticles for Sensitive Cancer Detection

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Chemical Synthesis of Monodisperse Magnetic Nanoparticles for Sensitive Cancer Detection

Content Provider	Springer Nature Link
Author	Sun, Shouheng
Copyright Year	2013
Abstract	This short tutorial review highlights the advance in high temperature solution phase chemical synthesis of monodisperse magnetic nanoparticles (MNPs), especially iron oxide NPs, as contrast enhancement agents for cancer detection by magnetic resonance imaging (MRI). It introduces briefly the unique nanomagnetism of MNPs required for MRI. It then summarizes some typical methods used to prepare monodisperse Fe$_{3}$O$_{4}$ and ferrite MFe$_{2}$O$_{4}$ MNPs from high temperature organic phase reaction with controlled magnetic properties. It further outlines the chemistry used to make these MNPs biocompatible and target-specific. Finally it presents two examples to demonstrate the MNP control achieved from chemical synthesis for sensitive detection of cancer.
Starting Page	33
Ending Page	38
Page Count	6
File Format	PDF
ISSN	15741443
Journal	Journal of Inorganic and Organometallic Polymers and Materials
Volume Number	24
Issue Number	1
e-ISSN	15741451
Language	English
Publisher	Springer US
Publisher Date	2013-09-18
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Iron oxide nanoparticles Solution phase synthesis Nanoparticle functionalization Magnetic resonance imaging Cancer detection Inorganic Chemistry Organic Chemistry Polymer Sciences
Content Type	Text
Resource Type	Article
Subject	Materials Chemistry Polymers and Plastics

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