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  1. Journal of Materials Science: Materials in Medicine
  2. Journal of Materials Science: Materials in Medicine : Volume 24
  3. Journal of Materials Science: Materials in Medicine : Volume 24, Issue 6, June 2013
  4. Electrospinning of PCL/PVP blends for tissue engineering scaffolds
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Journal of Materials Science: Materials in Medicine : Volume 28
Journal of Materials Science: Materials in Medicine : Volume 27
Journal of Materials Science: Materials in Medicine : Volume 26
Journal of Materials Science: Materials in Medicine : Volume 25
Journal of Materials Science: Materials in Medicine : Volume 24
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 12, December 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 11, November 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 10, October 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 9, September 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 8, August 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 7, July 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 6, June 2013
Editorial ( Journal of Materials Science: Materials in Medicine , Volume 24 , Issue 6 )
Calcium orthophosphates in dentistry
Effects of Ca on microstructure, mechanical and corrosion properties and biocompatibility of Mg–Zn–Ca alloys
Synthesis of a disulfide cross-linked polygalacturonic acid hydrogel for biomedical applications
Biodegradable β-tricalcium phosphate cement with anti-washout property based on chelate-setting mechanism of inositol phosphate
Creep and fatigue behavior of a novel 2-component paste-like formulation of acrylic bone cements
Thermal properties and surface reactivity in simulated body fluid of new strontium ion-containing phosphate glasses
A novel biomimetic analysis system for quantitative characterisation of sclerosing foams used for the treatment of varicose veins
Electrospinning of PCL/PVP blends for tissue engineering scaffolds
Effect of MgO nanofillers on burst release reduction from hydrogel nanocomposites
Long-term biocompatibility evaluation of 0.5 % zinc containing hydroxyapatite in rabbits
Size-dependent antibacterial activities of silver nanoparticles against oral anaerobic pathogenic bacteria
Cross-linked hyaluronic acid sub-micron particles: in vitro and in vivo biodistribution study in cancer xenograft model
Antimicrobial activity of silica coated silicon nano-tubes (SCSNT) and silica coated silicon nano-particles (SCSNP) synthesized by gas phase condensation
Synthesis of hybrid sol–gel materials and their biological evaluation with human mesenchymal stem cells
Biocompatibility studies of low temperature nitrided and collagen-I coated AISI 316L austenitic stainless steel
Comparison of the effects of Mg–6Zn and titanium on intestinal tract in vivo
Spheroid model study comparing the biocompatibility of Biodentine and MTA
Comparative study of three types of polymer materials co-cultured with bone marrow mesenchymal stem cells for use as a myocardial patch in cardiomyocyte regeneration
Immobilized MWCNT support osteogenic cell culture
The influence of surface nanoroughness of electrospun PLGA nanofibrous scaffold on nerve cell adhesion and proliferation
Supermacroporous poly(vinyl alcohol)-carboxylmethyl chitosan-poly(ethylene glycol) scaffold: an in vitro and in vivo pre-assessments for cartilage tissue engineering
Improved angiogenic cell penetration in vitro and in vivo in collagen scaffolds with internal channels
Rapidly stopping hemorrhage by enhancing blood clotting at an opened wound using chitosan/polylactic acid/polycaprolactone wound dressing device
Synthesis of a novel tertiary amine containing urethane dimethacrylate monomer (UDMTA) and its application in dental resin
Investigation of 2D and 3D electrospun scaffolds intended for tendon repair
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 5, May 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 4, April 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 3, March 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 2, February 2013
Journal of Materials Science: Materials in Medicine : Volume 24, Issue 1, January 2013
Journal of Materials Science: Materials in Medicine : Volume 23
Journal of Materials Science: Materials in Medicine : Volume 22
Journal of Materials Science: Materials in Medicine : Volume 21
Journal of Materials Science: Materials in Medicine : Volume 20
Journal of Materials Science: Materials in Medicine : Volume 19
Journal of Materials Science: Materials in Medicine : Volume 18
Journal of Materials Science: Materials in Medicine : Volume 17
Journal of Materials Science: Materials in Medicine : Volume 16
Journal of Materials Science: Materials in Medicine : Volume 15
Journal of Materials Science: Materials in Medicine : Volume 14
Journal of Materials Science: Materials in Medicine : Volume 13
Journal of Materials Science: Materials in Medicine : Volume 12
Journal of Materials Science: Materials in Medicine : Volume 11
Journal of Materials Science: Materials in Medicine : Volume 10
Journal of Materials Science: Materials in Medicine : Volume 9
Journal of Materials Science: Materials in Medicine : Volume 8

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Electrospinning of PCL/PVP blends for tissue engineering scaffolds

Content Provider Springer Nature Link
Author Kim, Gyeong Man Le, Kim Huyen Trang Giannitelli, Sara Maria Lee, Yu Jin Rainer, Alberto Trombetta, Marcella
Copyright Year 2013
Abstract Currently, one of the main drawbacks of using poly(ε-caprolactone) in the biomedical and pharmaceutical fields is represented by its low biodegradation rate. To overcome this limitation, electrospinning of PCL blended with a water-soluble poly(N-vinyl-2-pyrrolidone) was used to fabricate scaffolds with tunable fiber surface morphology and controllable degradation rates. Electrospun scaffolds revealed a highly immiscible blend state. The incorporated PVP phase was dispersed as inclusions within the electrospun fibers, and then easily extracted by immersing them in cell culture medium, exhibiting nanoporosity on the fiber surface. As a striking result, nanoporosity facilitated not only fiber biodegradation rates, but also improved cell attachment and spreading on the blend electrospun scaffolds. The present findings demonstrate that simultaneous electrospinning technique for PCL with water-soluble PVP provides important insights for successful tuning biodegradation rate for the PCL electrospun scaffolds but not limited to expand other high valuable biocompatible polymers for the future biomedical applications, ranging from tissue regeneration to controlled drug delivery.
Starting Page 1425
Ending Page 1442
Page Count 18
File Format PDF
ISSN 09574530
Journal Journal of Materials Science: Materials in Medicine
Volume Number 24
Issue Number 6
e-ISSN 15734838
Language English
Publisher Springer US
Publisher Date 2013-03-07
Publisher Place Boston
Access Restriction Subscribed
Subject Keyword Biomaterials Polymer Sciences Ceramics, Glass, Composites, Natural Methods Metallic Materials Characterization and Evaluation of Materials Surfaces and Interfaces, Thin Films
Content Type Text
Resource Type Article
Subject Biomaterials Biophysics Bioengineering Biomedical Engineering
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