NDLI: The properties of biomimetically processed calcium phosphate on bioactive ceramics and their response on bone cells

Content Provider	Springer Nature Link
Author	Vaahtio, M. Peltola, T. Hentunen, T. Ylänen, H. Areva, S. Wolke, J. Salonen, J. I.
Copyright Year	2006
Abstract	This study looks for grounds to alter the chemical composition (phosphate, calcium, silica and carbonate), dissolution properties, structure and nanotopography of the biomimetically processed surfaces on bioactive ceramics to optimize their shown ability to influence bone cell behaviour and production of new bone. In the bone environment desirable characteristic of these materials is their ability to be remodeled by natural osteoclastic resorption. Different silica and carbonate containing calcium phosphate layers were prepared on bioactive glasses 9 (S53P4) and 1-98 (S53P2) and sol-gel processed pure silica SiO$_{2}$ in C- and R-SBF (conventional and revised simulated body fluid) for varying periods of time. It was shown that in R-SBF the CaP layer formed faster compared to C-SBF. The CaP layer in the R-SBF contained more carbonate (CO$_{3}$ $^{2−}$) compared to that formed with the same immersion time in C-SBF. The CaP so formed in R-SBF with faster precipitation is more amorphous than the bonelike HCA formed in C-SBF. The results indicate that the most suitable surface for both osteoblasts and osteoclasts was found to be an amorphous CaP having mesoporous nanotopography and proper dissolution rate of calcium and silica.
Starting Page	1113
Ending Page	1125
Page Count	13
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	17
Issue Number	11
e-ISSN	15734838
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2006-11-22
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Polymer Sciences Biomaterials Metallic Materials Characterization and Evaluation Materials Ceramics, Glass, Composites, Natural Methods Surfaces and Interfaces, Thin Films
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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