NDLI: Titanium oxide nanotubes for bone regeneration

Content Provider	Springer Nature Link
Author	Kubota, Suguru Johkura, Kohei Asanuma, Kazuhiko Okouchi, Yasumitsu Ogiwara, Naoko Sasaki, Katsuri Kasuga, Tomoko
Copyright Year	2004
Abstract	Titanium oxide nanotubes with Ca ions on their surfaces were prepared as 2 mm cylindrical inserts and placed into surgically created bone defects in the femurs of Wistar rats. On day 3, fibroblast-like cells were present on the surface of the nanotube inserts and fibers were observed by scanning electron microscopy (SEM). On day 7, cells with alkaline phosphatase activity were present and identified as osteoblasts by SEM and transmission electron microscopy. New bone matrices were observed in and around the porous nanotube inserts by light microscopy. Compared with clinically used hydroxyapatite and tricalcium phosphate, β-titanium oxide nanotubes promote faster acquisition and development of osteoblasts and bone tissues and have better bone regenerating ability after one week.
Starting Page	1031
Ending Page	1035
Page Count	5
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	15
Issue Number	9
e-ISSN	15734838
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2004-01-01
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Biotechnology Polymer Sciences Characterization and Evaluation Materials
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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Titanium oxide nanotubes for bone regeneration