NDLI: Fabrication and characterization of porous Ti–7.5Mo alloy scaffolds for biomedical applications

Content Provider	Springer Nature Link
Author	Hsu, Hsueh Chuan Hsu, Shih Kuang Tsou, Hsi Kai Wu, Shih Ching Lai, Tsung Hsuan Ho, Wen Fu
Copyright Year	2013
Abstract	Porous titanium and titanium alloys are promising scaffolds for bone tissue engineering, since they have the potential to provide new bone tissue ingrowth abilities and low elastic modulus to match that of natural bone. In the present study, porous Ti–7.5Mo alloy scaffolds with various porosities from 30 to 75 % were successfully prepared through a space-holder sintering method. The yield strength and elastic modulus of a Ti–7.5Mo scaffold with a porosity of 50 % are 127 MPa and 4.2 GPa, respectively, being relatively comparable to the reported mechanical properties of natural bone. In addition, the porous Ti–7.5Mo alloy exhibited improved apatite-forming abilities after pretreatment (with NaOH or NaOH + water) and subsequent immersion in simulated body fluid (SBF) at 37 °C. After soaking in an SBF solution for 21 days, a dense apatite layer covered the inner and outer surfaces of the pretreated porous Ti–7.5Mo substrates, thereby providing favorable bioactive conditions for bone bonding and growth. The preliminary cell culturing result revealed that the porous Ti–7.5Mo alloy supported cell attachment.
Starting Page	645
Ending Page	657
Page Count	13
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	24
Issue Number	3
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2013-01-13
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Biomaterials Polymer Sciences Ceramics, Glass, Composites, Natural Methods Metallic Materials Characterization and Evaluation of Materials Surfaces and Interfaces, Thin Films
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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