NDLI: Differentiation of human mesenchymal stem cells on plasma-treated polyetheretherketone

Content Provider	Springer Nature Link
Author	Waser Althaus, Jasmin Salamon, Achim Waser, Marcus Padeste, Celesti Kreutzer, Michael Pieles, Uwe Müller, Bert Peters, Kirsten
Copyright Year	2013
Abstract	Polyetheretherketone (PEEK) generally exhibits physical and chemical characteristics that prevent osseointegration. To activate the PEEK surface, we applied oxygen and ammonia plasma treatments. These treatments resulted in surface modifications, leading to changes in nanostructure, contact angle, electrochemical properties and protein adhesion in a plasma power and process gas dependent way. To evaluate the effect of the plasma-induced PEEK modifications on stem cell adhesion and differentiation, adipose tissue-derived mesenchymal stem cells (adMSC) were seeded on PEEK specimens. We demonstrated an increased adhesion, proliferation, and osteogenic differentiation of adMSC in contact to plasma-treated PEEK. In dependency on the process gas (oxygen or ammonia) and plasma power (between 10 and 200 W for 5 min), varying degrees of osteogenic differentiation were induced. When adMSC were grown on 10 and 50 W oxygen and ammonia plasma-treated PEEK substrates they exhibited a doubled mineralization degree relative to the original PEEK. Thus plasma treatment of PEEK specimens induced changes in surface chemistry and topography and supported osteogenic differentiation of adMSC in vitro. Therefore plasma treated PEEK holds perspective for contributing to osseointegration of dental and orthopedic load-bearing PEEK implants in vivo.
Starting Page	515
Ending Page	525
Page Count	11
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	25
Issue Number	2
e-ISSN	15734838
Language	English
Publisher	Springer US
Publisher Date	2013-11-08
Publisher Place	Boston
Access Restriction	Subscribed
Subject Keyword	Biomaterials Polymer Sciences Ceramics, Glass, Composites, Natural Methods Metallic Materials Characterization and Evaluation of Materials Surfaces and Interfaces, Thin Films
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

3D environment on human mesenchymal stem cells differentiation for bone tissue engineering

Emulsion electrospun nanofibers as substrates for cardiomyogenic differentiation of mesenchymal stem cells

Cytocompatibility evaluation of different biodegradable magnesium alloys with human mesenchymal stem cells

Modulation of osteogenic, adipogenic and myogenic differentiation of mesenchymal stem cells by submicron grooved topography

Morphology and adhesion of mesenchymal stem cells on PLLA, apatite and apatite/collagen surfaces

Increased response of Vero cells to PHBV matrices treated by plasma

The enhanced effect of surface microstructured porous titanium on adhesion and osteoblastic differentiation of mesenchymal stem cells

Effect of direct RGD incorporation in PLLA nanofibers on growth and osteogenic differentiation of human mesenchymal stem cells

Stem cell plasticity, osteogenic differentiation and the third dimension

Differentiation of human mesenchymal stem cells on plasma-treated polyetheretherketone

Similar Documents

3D environment on human mesenchymal stem cells differentiation for bone tissue engineering

Emulsion electrospun nanofibers as substrates for cardiomyogenic differentiation of mesenchymal stem cells

Cytocompatibility evaluation of different biodegradable magnesium alloys with human mesenchymal stem cells

Modulation of osteogenic, adipogenic and myogenic differentiation of mesenchymal stem cells by submicron grooved topography

Morphology and adhesion of mesenchymal stem cells on PLLA, apatite and apatite/collagen surfaces

Increased response of Vero cells to PHBV matrices treated by plasma

The enhanced effect of surface microstructured porous titanium on adhesion and osteoblastic differentiation of mesenchymal stem cells

Effect of direct RGD incorporation in PLLA nanofibers on growth and osteogenic differentiation of human mesenchymal stem cells

Stem cell plasticity, osteogenic differentiation and the third dimension

Differentiation of human mesenchymal stem cells on plasma-treated polyetheretherketone