NDLI: Corrosion resistance studies on grain-boundary etched drug-eluting stents

Content Provider	Springer Nature Link
Author	Rettig, Ralf Kunze, Julia Stöver, Michael Wintermantel, Erich Virtanen, Sannakaisa
Copyright Year	2007
Abstract	In this paper we compare the influence of different microstructures on the corrosion resistance of new drug-eluting stainless steel stents, which have been produced by grain-boundary-selective electrochemical etching processes. The morphology of the stent surfaces was analysed by scanning electron microscopy (SEM), and the surface composition was investigated with Auger electron spectroscopy (AES) as well as with energy dispersive X-ray analysis (EDX). The passivity of the different microstructured stents was studied by cyclovoltammetry in Ringer solution. Release of nickel and chromium was assessed after potentiostatic experiments in Ringer solution by analysing the collected electrolyte with AAS. For stents produced by different two-step etching procedures bringing about ideal morphologies regarding the mechanical and biological properties of the surface, no significant differences in the passivation behaviour could be observed. A two-step process using first nitric acid and oxalic acid in a second step produces stent surfaces with very good corrosion properties: electrochemical analysis shows that the range of stable passivity is the same as for conventional stent surfaces, and low rates of nickel and chromium release are observed. The etching procedures do not seem to change the surface oxide layer composition.
Starting Page	1377
Ending Page	1387
Page Count	11
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	18
Issue Number	7
e-ISSN	15734838
Language	English
Publisher	Kluwer Academic Publishers-Plenum Publishers
Publisher Date	2007-02-03
Publisher Place	New York
Access Restriction	Subscribed
Subject Keyword	Surfaces and Interfaces, Thin Films Ceramics, Glass, Composites, Natural Methods Metallic Materials Polymer Sciences Characterization and Evaluation of Materials Biomaterials
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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