NDLI: Hydrogel-elastomer composite biomaterials: 2. Effects of aging methacrylated gelatin solutions on the preparation and physical properties of interpenetrating polymer networks

Content Provider	Springer Nature Link
Author	Peng, Henry T. Mok, Michelle Martineau, Lucie Shek, Pang N.
Copyright Year	2007
Abstract	This study was conducted to understand the effects of aging methacrylated gelatin solutions on the properties of gelatin-HydroThane$^{TM}$ Interpenetrating Polymer Network (IPN) films. The latter were prepared from methacrylated gelatin solutions that were either freshly made or stored at different concentrations and temperatures for various periods. The morphology, swelling stability and mechanical properties of the IPNs were then accordingly characterized. The IPNs prepared with aged solutions showed a reduced phase separation; changed from a network-like structure to a continuous phase structure; and demonstrated higher swelling stabilities and higher elasticity under optimal aging conditions, compared to the IPN prepared with a fresh methacrylated gelatin solution. An increase in viscosity and a change in phase transition of aged methacrylated gelatin solutions were also observed, presumably due to the physical structuring of methacrylated gelatin chains (e.g., by the formation of a helix structure), thus altering the resulting IPN characteristics. A better understanding of the effects of aging methacrylated gelatin solution on the formation and properties of gelatin-HydroThane$^{TM}$ IPNs should enable us to further develop our composite biomaterials for different dressing applications.
Starting Page	1025
Ending Page	1035
Page Count	11
File Format	PDF
ISSN	09574530
Journal	Journal of Materials Science: Materials in Medicine
Volume Number	18
Issue Number	6
e-ISSN	15734838
Language	English
Publisher	Kluwer Academic Publishers-Plenum Publishers
Publisher Date	2007-01-23
Publisher Place	New York
Access Restriction	Subscribed
Subject Keyword	Surfaces and Interfaces, Thin Films Ceramics, Glass, Composites, Natural Methods Metallic Materials Polymer Sciences Characterization and Evaluation of Materials Biomaterials
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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