NDLI: Noninvasive diagnostics of skin microphysical parameters based on spatially resolved diffuse reflectance spectroscopy

Content Provider	Springer Nature Link
Author	Lisenko, S. A. Kugeiko, M. M.
Copyright Year	2013
Abstract	The ability to determine noninvasively microphysical parameters (MPPs) of skin characteristic of malignant melanoma was demonstrated. The MPPs were the melanin content in dermis, saturation of tissue with blood vessels, and concentration and effective size of tissue scatterers. The proposed method was based on spatially resolved spectral measurements of skin diffuse reflectance and multiple regressions between linearly independent measurement components and skin MPPs. The regressions were established by modeling radiation transfer in skin with a wide variation of its MPPs. Errors in the determination of skin MPPs were estimated using fiber-optic measurements of its diffuse reflectance at wavelengths of commercially available semiconductor diode lasers (578, 625, 660, 760, and 806 nm) at source–detector separations of 0.23–1.38 mm.
Starting Page	934
Ending Page	943
Page Count	10
File Format	PDF
ISSN	00219037
Journal	Journal of Applied Spectroscopy
Volume Number	79
Issue Number	6
e-ISSN	15738647
Language	English
Publisher	Springer US
Publisher Date	2013-02-03
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	skin melanoma microphysical parameters diffuse reflectance fiber-optic measurements inverse problem multiple regressions Atomic/Molecular Structure and Spectra Analytical Chemistry
Content Type	Text
Resource Type	Article
Subject	Spectroscopy Condensed Matter Physics

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Noninvasive diagnostics of skin microphysical parameters based on spatially resolved diffuse reflectance spectroscopy