NDLI: Estimation of bronchial tree zones involved in the formation of human forced expiratory wheezes

Content Provider	Springer Nature Link
Author	Korenbaum, V. I. Pochekutova, I. A. Safrova, M. A.
Copyright Year	2015
Abstract	Forced expiratory wheezes (FEWs) are used for the diagnosis of bronchial obstruction; however, there is no clarity about the mechanisms and possible localization of their formation. The aim of the study was to clarify the sites of FEW formation at bronchial levels in different types of dynamic compression. The peak frequencies of the mid- (400–600 Hz) and high-frequency (more than 600 Hz) FEWs of the maximum power and the flow rate at the mouth were measured in a sample of 85 healthy male volunteers whose ages varied between 16 and 23 years. Strouhal coefficients were calculated for various bronchial tree levels according to Weibel’s morphometry. It is shown that, for FEWs formed by vortex shedding with Strouhal coefficients 0.2–0.3, the trend is to shift their formation zone to the proximal region with an increase in the degree of dynamic compression of the airways. For the most reliable estimates of dynamic compression, the main region of formation of mid-frequency FEWs is the area of exit of the intrathoracic portion of the trachea into its outer part and bifurcation of the trachea, while the most probable formation zone of early high-frequency FEWs is bifurcations of the primary bronchi and the trachea.
Starting Page	54
Ending Page	61
Page Count	8
File Format	PDF
ISSN	03621197
Journal	Human Physiology
Volume Number	41
Issue Number	1
e-ISSN	16083164
Language	English
Publisher	Pleiades Publishing
Publisher Date	2015-02-14
Publisher Place	Moscow
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	forced expiration wheezes peak frequency statistical modeling vortex shedding Strouhal coefficient dynamic compression Life Sciences Human Physiology Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Physiology Physiology (medical)

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