NDLI: Mechanisms of QRS voltage changes on ECG of healthy subjects during the exercise test

Content Provider	Springer Nature Link
Author	Saltykova, M. M.
Copyright Year	2015
Abstract	Electrocardiography is the most commonly used technique for detection stress-induced myocardial ischemia. However, the sensitivity of ECG criteria is not high. One of the major problems is the difficulty in differentiating ECG changes caused by various factors. The aim of this study was to evaluate the dependence of the QRS voltage changes on ECG during exercise on the parameters of central hemodynamics, to analyze gender particularities, and to reveal the mechanisms causing these changes. To eliminate the effect of changes in cardiomyocyte transmembrane potentials under the influence of neurotransmitters of the autonomic nervous system during stepwise increasing exercises and/or due to adenosine triphosphate (ATP) deficiency resulting from inadequate myocardial blood flow, only apparently healthy subjects not older than 35 years (seven men and seven women) were involved in the study and only the periods of ventricular depolarization (QRS complex on ECG) were included in the analysis. We compared the changes of QRS waves during exercise sessions with two upper and one lower limb in both men and women. The moment of force developed during the exercise was twice greater in the exercise with one leg relative to the exercise with two arms. The responses of the heart rate and the systolic blood pressure were similar. The amplitude of the S-wave in the left precordial leads significantly increased in both sessions without significant difference between augmentations in the sessions and in groups of men and women. A significant dependence of the S-wave augmentation at the end of session and the peak systolic blood pressure was revealed. In addition, the QRS changes during the exercise with vertical and horizontal torso position were compared to assess the effect of diastolic blood pressure and displacement of the diaphragm and heart rotation due to an increase in the abdominal pressure during the last steps of exercise. The obtained results allow us to exclude the effect of changes in the heart position and size, as well as the exercise load on the revealed S-wave changes and to conclude that parameter depends on the systolic blood pressure.
Starting Page	62
Ending Page	69
Page Count	8
File Format	PDF
ISSN	03621197
Journal	Human Physiology
Volume Number	41
Issue Number	1
e-ISSN	16083164
Language	English
Publisher	Pleiades Publishing
Publisher Date	2015-02-14
Publisher Place	Moscow
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	ECG exercise stress test exercise-induced QRS voltage changes Life Sciences Human Physiology Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Physiology Physiology (medical)

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