NDLI: Systemic and pulmonary hemodynamics assessed with a lumped-parameter heart-arterial interaction model

Content Provider	Springer Nature Link
Author	Segers, Patrick Stergiopulos, Nikos Westerhof, Nico Wouters, Patrick Kolh, Philippe Verdonck, Pascal
Copyright Year	2003
Abstract	Arterial pressure and flow result from the interaction between the (actively) ejecting ventricle and the (passive) arterial circulation. The main objective was to construct a model, accounting for this interaction, that is simple enough so that (i) model parameters can be derived from data measured in experimental and/or clinical conditions, and (ii) the model can be applied to support the analysis and interpretation of these data. It is demonstrated how an established conceptual model of ventricular function (the time-varying elastance) can be coupled to a four-element windkessel model of the arterial system to yield an elegant model of heart-arterial interaction. The coupling leads to a set of three ordinary differential equations. The model allows the study of the effect of changes in cardiac and/or arterial properties on arterial pressure and flow. As an illustration, cardiac and arterial model parameters are derived from measured experimental data in the systemic circulation of a pig and in the pulmonary circulation of a dog. It is evaluated how well measured cardiac and arterial function actually adhere to their assumed theoretical models (time-varying elastance and four-element windkessel model). It is further assessed how well the simple model of heart-arterial interaction describes systemic and pulmonary hemodynamics by comparing simulated and measured experimental data. The limitations and pitfalls of the model, as well as possible applications in the clinical field, are discussed.
Starting Page	185
Ending Page	199
Page Count	15
File Format	PDF
ISSN	00220833
Journal	Journal of Engineering Mathematics
Volume Number	47
Issue Number	3-4
e-ISSN	15732703
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2003-01-01
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Numeric Computing Analysis Applications of Mathematics Mathematical Modeling and Industrial Mathematics Mechanics
Content Type	Text
Resource Type	Article
Subject	Mathematics Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Mathematical modelling of arterial fluid dynamics

The role of hemodynamics in the development of the outflow tract of the heart

Flow into an Arterial Branch Model

The reservoir pressure concept: the 3-element windkessel model revisited? Application to the Asklepios population study

Interaction of free-surface waves with floating flexible strips

Interaction of free-surface waves with a floating dock

A mathematical model for drying paint layers

Introductory remarks

Introductory Remarks

Systemic and pulmonary hemodynamics assessed with a lumped-parameter heart-arterial interaction model

Similar Documents

Mathematical modelling of arterial fluid dynamics

The role of hemodynamics in the development of the outflow tract of the heart

Flow into an Arterial Branch Model

The reservoir pressure concept: the 3-element windkessel model revisited? Application to the Asklepios population study

Interaction of free-surface waves with floating flexible strips

Interaction of free-surface waves with a floating dock

A mathematical model for drying paint layers

Introductory remarks

Introductory Remarks

Systemic and pulmonary hemodynamics assessed with a lumped-parameter heart-arterial interaction model