NDLI: Blood flow in the human ascending aorta: a combined MRI and CFD study

Content Provider	Springer Nature Link
Author	Leuprecht, Armin Kozerke, Sebastian Boesiger, Peter Perktold, Karl
Copyright Year	2003
Abstract	Blood flow through the ascending aorta of two individuals is studied numerically. Realistic flow simulation is enabled by the combination of MRI and CFD. The aim of this study is the validation of the calculated flow field and, on the other hand, a comparison between flow distal to an artificial heart valve and native flow of a healthy volunteer. Three-dimensional, time-dependent computer models of the human ascending aorta were reconstructed from three-directional data sets acquired by MRI in the subjects studied. MRI velocity measurements downstream of the aortic valve provided the inflow conditions for the computational study. The pulsatile flow is described by the ALE-modified Navier-Stokes equations with respect to the time-varying flow domain. The numerical approach applies our own developed finite-element solver. During systolic acceleration the flow patterns distal to the valves do not show major differences between the two configurations. During flow deceleration, however, a significant influence of the disturbed inflow conditions can be found in the whole segment. Using the methods proposed, simulation of blood flow in the ascending aorta of the two subjects could be successfully performed. There was good qualitative agreement of blood velocities predicted by CFD and velocity data measured by MRI. In conclusion, the approach described herein might offer a new way towards an improved assessment of detailed in vivo flow conditions and alterations of blood flow associated with heart valve prostheses in particular. Combining CFD and MRI potentially extends the quantification of hemodynamic variables in vivo at a scale beyond the resolution limit inherent to MRI.
Starting Page	387
Ending Page	404
Page Count	18
File Format	PDF
ISSN	00220833
Journal	Journal of Engineering Mathematics
Volume Number	47
Issue Number	3-4
e-ISSN	15732703
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2003-01-01
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Numeric Computing Analysis Applications of Mathematics Mathematical Modeling and Industrial Mathematics Mechanics
Content Type	Text
Resource Type	Article
Subject	Mathematics Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

One-dimensional models for blood flow in arteries

Flow efficiency of perforated systems – a combined analytical and numerical treatment

A numerical study of pulsatile blood flow in an eccentric catheterized artery using a fast algorithm

Unsteady laminar flow over a rough surface

The decay of suddenly blocked flow in a curved pipe

Fluid flow through various branching tubes

Unsteady Fully-Developed Flow in a Curved Pipe

Stokes flow in a mixer with changing geometry

Shear flow over a particulate or fibrous plate

Blood flow in the human ascending aorta: a combined MRI and CFD study

Similar Documents

One-dimensional models for blood flow in arteries

Flow efficiency of perforated systems – a combined analytical and numerical treatment

A numerical study of pulsatile blood flow in an eccentric catheterized artery using a fast algorithm

Unsteady laminar flow over a rough surface

The decay of suddenly blocked flow in a curved pipe

Fluid flow through various branching tubes

Unsteady Fully-Developed Flow in a Curved Pipe

Stokes flow in a mixer with changing geometry

Shear flow over a particulate or fibrous plate

Blood flow in the human ascending aorta: a combined MRI and CFD study