NDLI: Assessment of selenium toxicity on the life cycle of Caenorhabditis elegans

Content Provider	Springer Nature Link
Author	Li, Wen Hsuan Ju, Yun Ru Liao, Chung Min Liao, Vivian Hsiu Chuan
Copyright Year	2014
Abstract	Selenium (Se) is a growing problem of global concern. Se can cause adverse effects on reproductive systems, which have been linked to declines in animal populations. The soil nematode Caenorhabditis elegans (C. elegans) is a ubiquitous soil organism that is increasingly utilized as a model organism in aquatic and soil toxicology. In the present study, the experimental data for individual body length, survival rate, brood size, and hatching rate were used to evaluate the possible effects of selenite [Se(IV)] on C. elegans. A stage-classified matrix model was applied to the experimental data to provide information on the population dynamics of C. elegans and to assess the Se(IV)-affected asymptotic population growth rate. Estimates of the survival probability showed significant decreases in survival at all stages when C. elegans was exposed to Se(IV). The growth probability of C. elegans in the L1 stage showed the most significant decline, from 0.11 h−1 (for the control) to 0.04 h−1 [for exposure to 3 mM Se(IV)]. These results showed that Se(IV) has a profound impact on C. elegans population dynamics. The asymptotic population growth rate (λ) was found to range from 1.00 to 0.64 h−1 for increasing Se(IV) concentrations, implying a potential risk of population decrease for C. elegans exposure to a Se(IV)-contaminated environment. Our study shows how a mechanistic view based on the Se(IV) effects on the soil nematode C. elegans can promote a life cycle toxicity assessment. An important implication of this analysis is that mathematical models can be used to produce a population stage structure, to give clarity to the analysis of the key population-level endpoint (the asymptotic population growth rate) of population dynamics, and to evaluate the influences for the response of other species to environmental Se. These models sequentially provide candidate environmental criteria for the evaluation of the population impact of Se.
Starting Page	1245
Ending Page	1253
Page Count	9
File Format	PDF
ISSN	09639292
Journal	Ecotoxicology
Volume Number	23
Issue Number	7
e-ISSN	15733017
Language	English
Publisher	Springer US
Publisher Date	2014-06-07
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Selenium Caenorhabditis elegans Mathematical models Population Life cycle toxicity Environment Ecotoxicology Ecology Environmental Management
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Medicine Toxicology Management, Monitoring, Policy and Law

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Assessment of selenium toxicity on the life cycle of Caenorhabditis elegans.

Life cycle toxicity assessment of earthworms exposed to cadmium-contaminated soils

Consequences of a multi-generation exposure to uranium on Caenorhabditis elegans life parameters and sensitivity

Effects of a bioassay-derived ivermectin lowest observed effect concentration on life-cycle traits of the nematode Caenorhabditis elegans

ace-3 plays an important role in phoxim resistance in Caenorhabditis elegans

Rapid phenotypic changes in Caenorhabditis elegans under uranium exposure

Organic carbon source in formulated sediments influences life traits and gene expression of Caenorhabditis elegans

Food rationing affects dietary selenium bioaccumulation and life cycle performance in the mayfly Centroptilum triangulifer

Endocrine disruption in nematodes: effects and mechanisms

Assessment of selenium toxicity on the life cycle of Caenorhabditis elegans

Similar Documents

Assessment of selenium toxicity on the life cycle of Caenorhabditis elegans.

Life cycle toxicity assessment of earthworms exposed to cadmium-contaminated soils

Consequences of a multi-generation exposure to uranium on Caenorhabditis elegans life parameters and sensitivity

Effects of a bioassay-derived ivermectin lowest observed effect concentration on life-cycle traits of the nematode Caenorhabditis elegans

ace-3 plays an important role in phoxim resistance in Caenorhabditis elegans

Rapid phenotypic changes in Caenorhabditis elegans under uranium exposure

Organic carbon source in formulated sediments influences life traits and gene expression of Caenorhabditis elegans

Food rationing affects dietary selenium bioaccumulation and life cycle performance in the mayfly Centroptilum triangulifer

Endocrine disruption in nematodes: effects and mechanisms

Assessment of selenium toxicity on the life cycle of Caenorhabditis elegans