NDLI: A case–control study of childhood brain tumors and fathers’ hobbies: a Children’s Oncology Group study

Content Provider	Springer Nature Link
Author	Rosso, Andrea L. Hovinga, Mary E. Rorke Adams, Lucy B. Spector, Logan G. Bunin, Greta R.
Copyright Year	2008
Abstract	A comprehensive case–control study was conducted to evaluate parental risk factors for medulloblastoma (MB) and primitive neuroectodermal tumor (PNET). This analysis was conducted to evaluate associations between fathers’ hobbies and risk of their children developing MB/PNET. The hobbies chosen for study were those with similar exposures as occupations associated with childhood cancers.Cases were 318 subjects under six years of age at diagnosis between 1991 and 1997 and registered with the Children’s Cancer Group. An equal number of controls were selected through random digit dialing and individually matched to cases.In multivariate analyses, a significant association was seen for lawn care with pesticides [during pregnancy: odds ratio (OR) = 1.6, 95% confidence interval (CI): 1.0, 2.5; after birth: OR = 1.8, 95% CI: 1.2, 2.8] and a weak association was seen for stripping paint [during pregnancy: OR = 1.4, 95% CI: 0.8, 2.6; after birth: OR = 1.4, 95% CI: 0.7, 2.6].This study suggests that household exposures from hobbies, particularly pesticides, may increase risk of MB/PNET in children; previous research has been mostly limited to occupational exposures.
Starting Page	1201
Ending Page	1207
Page Count	7
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	19
Issue Number	10
e-ISSN	15737225
Language	English
Publisher	Springer Netherlands
Publisher Date	2008-06-17
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Case–control studies Brain neoplasms Medulloblastomas Child preschool Infant Hobbies Pesticides Hematology Epidemiology Public Health/Gesundheitswesen Oncology Biomedicine general Cancer Research
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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