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| Content Provider | Springer Nature Link |
|---|---|
| Author | Aune, Dagfinn Vieira, Ana Rita Chan, Doris Sau Man Navarro Rosenblatt, Deborah A. Vieira, Rui Greenwood, Darren C. Cade, Janet E. Burley, Victoria J. rat, Teresa |
| Copyright Year | 2012 |
| Abstract | Greater height has been associated with increased risk of several cancers, but epidemiological data on height and pancreatic cancer are inconclusive. We conducted a systematic review and meta-analysis of prospective studies to clarify these results.PubMed and several other databases were searched up to September 2011. Prospective studies of height and pancreatic cancer were included. Summary relative risks were estimated by the use of a random effects model.We identified twelve cohort studies that were included in the meta-analysis. The summary RR per 5-cm increase in height was 1.07 (95 % CI: 1.03–1.12, I 2 = 57 %). The results were similar among men and women. The summary estimate was attenuated when we included results from two pooled analyses together with these studies, summary RR = 1.03 (95 % CI: 1.00–1.07, I 2 = 44 %).This meta-analysis of cohort studies provides further evidence that greater adult attained height is associated with increased pancreatic cancer risk. However, given the unexplained heterogeneity, further studies are needed before a conclusion can be drawn. |
| Starting Page | 1213 |
| Ending Page | 1222 |
| Page Count | 10 |
| File Format | |
| ISSN | 09575243 |
| Journal | Cancer Causes & Control |
| Volume Number | 23 |
| Issue Number | 8 |
| e-ISSN | 15737225 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2012-06-12 |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Height Pancreatic cancer The Continuous Update Project Systematic review Meta-analysis Hematology Oncology Epidemiology Public Health/Gesundheitswesen Biomedicine general Cancer Research |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cancer Research Oncology |
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