NDLI: Serum levels of vitamin D, parathyroid hormone and calcium in relation to survival following breast cancer

Content Provider	Springer Nature Link
Author	Huss, Linnea Butt, Salma Borgquist, Signe Almquist, Martin Malm, Johan Manjer, Jonas
Copyright Year	2014
Abstract	Vitamin D, parathyroid hormone (PTH) and calcium in blood are correlated with each other. Previous studies have suggested vitamin D to have anti-proliferative effects on tumor cells, whereas PTH may have carcinogenic effects. A cancer disease may influence calcium levels in blood, but less is known about calcium and its potential effect on cancer risk and survival. The aim of this study was to examine pre-diagnostic levels of vitamin D (25OHD), PTH and calcium in relation to survival after breast cancer.The Malmö Diet and Cancer Study enrolled 17,035 women between 1991 and 1996. 672 patients developed incident invasive breast cancer up until 31 December 2006. Serum samples collected at baseline were analyzed for 25OHD, PTH and calcium. All patients were followed until 31 December 2010 using the Swedish Cause of Death Registry. The analytes were divided into tertiles and the risk of death from breast cancer was analyzed using an adjusted Cox proportional hazards analysis, yielding hazard ratios with 95 % confidence intervals.Levels of 25OHD and breast cancer mortality were associated in a u-shaped manner with the highest mortality among patients in the first (2.46: 1.38–4.37) and third tertiles (1.99: 1.14–3.49), as compared to the second. An inverse relation was found between calcium levels and breast cancer mortality, with the lowest mortality in the third tertile, (0.53: 0.30–0.92) as compared to the first. There was no clear association between PTH and breast cancer mortality.This study shows that pre-diagnostic 25OHD and calcium may affect survival following breast cancer.
Starting Page	1131
Ending Page	1140
Page Count	10
File Format	PDF
ISSN	09575243
Journal	Cancer Causes & Control
Volume Number	25
Issue Number	9
e-ISSN	15737225
Language	English
Publisher	Springer International Publishing
Publisher Date	2014-06-22
Publisher Place	Cham
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Breast cancer Calcium Mortality PTH Survival Vitamin D Cancer Research Biomedicine general Oncology Public Health Epidemiology Hematology
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Vitamin D, PTH, and calcium in relation to survival following prostate cancer

Serum levels of vitamin D, parathyroid hormone and calcium in relation to survival following breast cancer

Serum levels of vitamin D, parathyroid hormone and calcium in relation to survival following breast cancer

Serum calcium and breast cancer risk: results from a prospective cohort study of 7,847 women

Vitamin D, PTH, and calcium and tumor aggressiveness in prostate cancer: a prospective nested case–control study

Vitamin D, PTH, and calcium and the risk of prostate cancer: a prospective nested case–control study

Serum levels of 25-hydroxyvitamin D and survival in Norwegian patients with cancer of breast, colon, lung, and lymphoma: a population-based study

Adolescent dietary vitamin D and sun exposure in relation to benign breast disease

Associations of serum 25-hydroxyvitamin D with overall and breast cancer–specific mortality in a multiethnic cohort of breast cancer survivors

Serum levels of vitamin D, parathyroid hormone and calcium in relation to survival following breast cancer

Similar Documents

Vitamin D, PTH, and calcium in relation to survival following prostate cancer

Serum levels of vitamin D, parathyroid hormone and calcium in relation to survival following breast cancer

Serum levels of vitamin D, parathyroid hormone and calcium in relation to survival following breast cancer

Serum calcium and breast cancer risk: results from a prospective cohort study of 7,847 women

Vitamin D, PTH, and calcium and tumor aggressiveness in prostate cancer: a prospective nested case–control study

Vitamin D, PTH, and calcium and the risk of prostate cancer: a prospective nested case–control study

Serum levels of 25-hydroxyvitamin D and survival in Norwegian patients with cancer of breast, colon, lung, and lymphoma: a population-based study

Adolescent dietary vitamin D and sun exposure in relation to benign breast disease

Associations of serum 25-hydroxyvitamin D with overall and breast cancer–specific mortality in a multiethnic cohort of breast cancer survivors

Serum levels of vitamin D, parathyroid hormone and calcium in relation to survival following breast cancer