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| Content Provider | Springer Nature Link |
|---|---|
| Author | Szymańska, K. Matos, E. Hung, R. J. Wünsch Filho, V. Eluf Neto, J. Menezes, A. Daudt, A. W. Brennan, P. Boffetta, P. |
| Copyright Year | 2010 |
| Abstract | Cancers of the upper aerodigestive tract (UADT: oral cavity, oropharynx, hypopharynx, larynx, esophagus) have high incidence rates all over the world and they are especially frequent in some parts of Latin America. In this study, we have evaluated the role of the consumption of maté, a hot herb-based beverage, based on 1168 UADT squamous-cell carcinoma cases and 1,026 frequency-matched controls enrolled from four centers in Brazil and Argentina. The effect of maté drinking on the risk of head-and-neck cancers was borderline significant. A significant effect was observed only for cancer of the esophagus (OR 3.81 (95% CI 1.75–8.30)). While duration of maté drinking was associated with the risk of all UADT cancers, the association with cumulative maté consumption was restricted to esophageal cancer (p-value of linear trend 0.006). The analyses of temperature at which maté was drunk were not conclusive. The increased risk associated with maté drinking was more evident in never-smokers and never-alcohol drinkers than in other individuals. Our study strengthens the evidence of an association between maté drinking and esophageal cancer; the hypothesis of an association with other UADT cancers remains to be clarified. |
| Starting Page | 1799 |
| Ending Page | 1806 |
| Page Count | 8 |
| File Format | |
| ISSN | 09575243 |
| Journal | Cancer Causes & Control |
| Volume Number | 21 |
| Issue Number | 11 |
| e-ISSN | 15737225 |
| Language | English |
| Publisher | Springer Netherlands |
| Publisher Date | 2010-07-10 |
| Publisher Place | Dordrecht |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | UADT Aerodigestive Upper aerodigestive tract South America Latin America Maté Cancer Risk Case–control study Hematology Epidemiology Public Health/Gesundheitswesen Oncology Biomedicine general Cancer Research |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cancer Research Oncology |
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