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| Content Provider | Springer Nature Link |
|---|---|
| Author | Cendrowski, Krzysztof Peruzynska, Magdalena Markowska Szczupak, Agata Chen, Xuecheng Wajda, Anna Lapczuk, Joanna Kurzawski, Mateusz Kalenczuk, Ryszard J. Drozdzik, Marek Mijowska, Ewa |
| Copyright Year | 2014 |
| Abstract | In this paper, we study synthesis and characteristics of mesoporous silica nanotubes modified by titanium dioxide, as well as their antimicrobial properties and influence on mitochondrial activity of mouse fibroblast L929. Nanocrystalized titania is confined in mesopores of silica nanotubes and its light activated antibacterial response is revealed. The analysis of the antibacterial effect on Escherichia coli. (ATCC 25922) shows strong enhancement during irradiation with the artificial visible and ultraviolet light in respect to the commercial catalyst and control sample free from the nanomaterials. In darkness, the mesoporous silica/titania nanostructures exhibited antibacterial activity dependent on the stirring speed of the suspension containing nanomaterials. Obtained micrograph proved internalization of the sample into the microorganism trough the cell membrane. The analysis of the mitochondrial activity and amount of lactate dehydrogenase released from mouse fibroblast cells L929 in the presence of the sample were determined with LDH and WST1 assays, respectively. The synthesized silica/titania antibacterial agent also exhibits pronounced photoinduced inactivation of the bacterial growth under the artificial visible and UV light irritation in respect to the commercial catalyst. Additionally, mesoporous silica/titania nanotubes were characterized in details by means of high resolution transmission electron microscopy (HR-TEM), XRD and BET Isotherm. |
| Starting Page | 449 |
| Ending Page | 458 |
| Page Count | 10 |
| File Format | |
| ISSN | 13872176 |
| Journal | Biomedical Microdevices |
| Volume Number | 16 |
| Issue Number | 3 |
| e-ISSN | 15728781 |
| Language | English |
| Publisher | Springer US |
| Publisher Date | 2014-03-28 |
| Publisher Place | Boston |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Mesoporous silica nanotubes Titanium dioxide Antibacterial agent Nanomaterials bactericidal properties Biomedical Engineering Biophysics and Biological Physics Nanotechnology Engineering Fluid Dynamics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Molecular Biology Biomedical Engineering |
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