NDLI: Mitochondrial ROS metabolism: 10 Years later

Content Provider	Springer Nature Link
Author	Andreyev, A. Y. Kushnareva, Y. E. Murphy, A. N. Starkov, A. A.
Copyright Year	2015
Abstract	The role of mitochondria in oxidative stress is well recognized, but many questions are still to be answered. This article is intended to update our comprehensive review in 2005 by highlighting the progress in understanding of mitochondrial reactive oxygen species (ROS) metabolism over the past 10 years. We review the recently identified or re-appraised sources of ROS generation in mitochondria, such as p66shc protein, succinate dehydrogenase, and recently discovered properties of the mitochondrial antioxidant system. We also reflect upon some controversies, disputes, and misconceptions that confound the field.
Starting Page	517
Ending Page	531
Page Count	15
File Format	PDF
ISSN	00062979
Journal	Biochemistry (Moscow)
Volume Number	80
Issue Number	5
e-ISSN	16083040
Language	English
Publisher	Pleiades Publishing
Publisher Date	2015-05-10
Publisher Place	Moscow
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	mitochondria reactive oxygen species p66shc succinate dehydrogenase dihydroorotate dehydrogenase ROS scavenging oxidative stress Biochemistry Bioorganic Chemistry Microbiology Biomedicine general
Content Type	Text
Resource Type	Article
Subject	Biochemistry Biophysics Geriatrics and Gerontology

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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Mitochondrial ROS metabolism: 10 Years later