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  1. Bulletin of Experimental Biology and Medicine
  2. Bulletin of Experimental Biology and Medicine : Volume 154
  3. Bulletin of Experimental Biology and Medicine : Volume 154, Issue 1, November 2012
  4. Release-Activity: A Long Way from Phenomenon to New Drugs
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Bulletin of Experimental Biology and Medicine : Volume 162
Bulletin of Experimental Biology and Medicine : Volume 161
Bulletin of Experimental Biology and Medicine : Volume 160
Bulletin of Experimental Biology and Medicine : Volume 159
Bulletin of Experimental Biology and Medicine : Volume 158
Bulletin of Experimental Biology and Medicine : Volume 157
Bulletin of Experimental Biology and Medicine : Volume 156
Bulletin of Experimental Biology and Medicine : Volume 155
Bulletin of Experimental Biology and Medicine : Volume 154
Bulletin of Experimental Biology and Medicine : Volume 154, Issue 6, April 2013
Bulletin of Experimental Biology and Medicine : Volume 154, Issue 5, March 2013
Bulletin of Experimental Biology and Medicine : Volume 154, Issue 4, February 2013
Bulletin of Experimental Biology and Medicine : Volume 154, Issue 3, January 2013
Bulletin of Experimental Biology and Medicine : Volume 154, Issue 2, December 2012
Bulletin of Experimental Biology and Medicine : Volume 154, Issue 1, November 2012
Peculiar Effects of Muscarinic M1, M2, and M3 Receptor Blockers on Cardiac Chronotropic Function in Neonatal Rats
Anxiety Level and Body Weight Changes in Rats Living in Overpopulated Cages
Dynamics of the Response to Variations in Dietary Choline Content in Rats
Effect of Somatostatin on Presynaptic and Postsynaptic Glutamate Receptors and Postsynaptic GABA Receptors in the Neurons of Rat Brain
Combined Influence of Information Load and Opioid Peptide Opilong on Hemostasis and Fibrinolysis in Rats
Reflections of Hunger and Satiation in the Structure of Temporal Organization of Slow Electrical and Spike Activities of Fundal and Antral Stomach Muscles in Rabbits
Functional Activity of Neutrophils in Diabetes Mellitus and Coronary Heart Disease: Role of Myeloperoxidase in the Development of Oxidative Stress
Structural Changes in Dendritic Loci and Protective Effect of Neurotrophic Factors from the Cerebral Cortex of Animals with Favorable Outcome of Experimental Hemorrhagic Stroke
Effect of Coenzyme Q10 on Proteomic Profile of Blood Plasma and Cytosolic and Microsomal Fractions of Rat Hepatocytes during Ontogeny
Superspiralization of Chiral Strings
Changes in the Level of Spontaneous DNA Damage in Whole Blood Leukocytes during Storage
Chitotriosidase Activity in the Blood Serum and Organs of Mice of Various Strains under the Infl uence of Chitin
Conformational Stability of Leukocyte Lactate Dehydrogenase in Healthy Men of Different Age
Cardioprotective Properties of Dimethyl Sulfoxide during Global Ischemia–Reperfusion of Isolated Rat Heart
Effects of Melatonin and Epithalamin on the Content of Protein and Lipid Peroxidation Products in Rat Cortex and Hippocampus under Conditions of Acute Hypoxia
Release-Activity: A Long Way from Phenomenon to New Drugs
Differential Analysis of Bactericidal Systems of Blood Serum with Recombinant Luminescent Escherichia coli and Bacillus subtilis Strains
Expression of Genes of Glutathione Transferase Isoforms GSTP1-1, GSTA4-4, and GSTK1-1 in Tumor Cells during the Formation of Drug Resistance to Cisplatin
Dependence of Blood Levels of HSP70 and HSP90 on Genotypes of HSP70, GSTT1, and GSTM1 Gene Polymorphism in Individuals Chronically Exposed to Mercury
Role of β2 Adrenoreceptor Gene Polymorphism in the Formation of Cold Hyperreactivity of the Airways in Asthmatics
Effects of HSP27 Chaperone on THP-1 Tumor Cell Apoptosis
Relationship between the Duration of G1 Period of Eukaryotic Cell Cycle and Age-Associated Changes in the Expression of Cyclin D1 and Nuclear Receptors
Reversible Zinc-Induced Injuries to Erythrocyte Membrane Nanostructure
Neurosteroids Dehydroepiandrosterone and Its Sulfate in Individuals with Personality Disorders Convicted of Serious Violent Crimes
Morphometric Characteristics of Terminal Villi of the Placenta in Pre-Eclampsia
Morphometric and Histochemical Characteristics of the Neocortex and Hippocampus of Experimentally Enlarged Rat Brain during the Suckling Period of Ontogeny
Vital Staining of Nerve Structures with Fluorescent Dyes and Optical Determination of Acetylcholine in the Somatic Muscle of the Earthworm Lumbricus terrestris
Distribution of H2S Synthesis Enzymes in the Walls of Cerebral Arteries in Rats
Effects of Exogenous Glycosaminoglycans on the Histological Structure of the Rat Bladder in Experimental Cystitis
Morphology and Functions of Erythrocyte Membranes in Pregnant Women after Exacerbation of Herpesvirus Infection
Immunohistochemical Detection of Two Neuronal Populations Involved in Two Different Episodes of Animal Cognitive Activity
Intravenous Xenotransplantation of Human Placental Mesenchymal Stem Cells to Rats: Comparative Analysis of Homing in Rat Brain in Two Models of Experimental Ischemic Stroke
Expression of Tight Junction Proteins by Umbilical Vein Epithelial Cells Co-Cultured with Allogenic Astrocytes
Effect of Hypoxia on Neural Induction in Colonies of Human Parthenogenetic Stem Cells
Possible Aspects of Using Cultured Stem Cell of Laboratory Primates in Experimental Medicine
Effect of Carnosine and Related Compounds on Proliferation of Cultured Rat Pheochromocytoma PC-12 Cells
Etoposide and Hypoxia Do Not Activate Apoptosis of Multipotent Mesenchymal Stromal Cells In Vitro
Methods of Detection of Mesenchymal Stem Cells in the Kidneys during Therapy of Experimental Renal Pathologies
Skin Regeneration after Chemical Burn under the Effect of Taxifolin-Based Preparations
Resident Cardiomyocyte Precursor Stem Cells in the Myocardium of Infants of the First Two Years of Life with Tetralogy of Fallot
The Use of Nanomechanic Sensor for Studies of Morphofunctional Properties of Lymphocytes from Healthy Donors and Patients with Chronic Lymphoblastic Leukemia
Scanning Electron Microscopy of Biosynthetic Wound Dressings Biocol
Erratum to: Increased 5-Bromo-2’-Deoxyuridine Incorporation in Various Brain Structures Following Passive Avoidance Training in Mice
Erratum to: Repeated Moderate Stress Stimulates the Production of Dehydroepiandrosterone Sulfate (DHEAS) and Reduces Corticosteroid Imbalance in Old Macaca Mulatta
Erratum to: Maternal Deprivation in Early Ontogeny Impairs Olfactory Learning with Mother’s Grooming Imitation in 129Sv Mice
Bulletin of Experimental Biology and Medicine : Volume 153
Bulletin of Experimental Biology and Medicine : Volume 152
Bulletin of Experimental Biology and Medicine : Volume 151
Bulletin of Experimental Biology and Medicine : Volume 150
Bulletin of Experimental Biology and Medicine : Volume 149
Bulletin of Experimental Biology and Medicine : Volume 148
Bulletin of Experimental Biology and Medicine : Volume 147
Bulletin of Experimental Biology and Medicine : Volume 146
Bulletin of Experimental Biology and Medicine : Volume 145
Bulletin of Experimental Biology and Medicine : Volume 144
Bulletin of Experimental Biology and Medicine : Volume 143
Bulletin of Experimental Biology and Medicine : Volume 142
Bulletin of Experimental Biology and Medicine : Volume 141
Bulletin of Experimental Biology and Medicine : Volume 140
Bulletin of Experimental Biology and Medicine : Volume 139
Bulletin of Experimental Biology and Medicine : Volume 138
Bulletin of Experimental Biology and Medicine : Volume 137
Bulletin of Experimental Biology and Medicine : Volume 136
Bulletin of Experimental Biology and Medicine : Volume 135
Bulletin of Experimental Biology and Medicine : Volume 134
Bulletin of Experimental Biology and Medicine : Volume 133
Bulletin of Experimental Biology and Medicine : Volume 132
Bulletin of Experimental Biology and Medicine : Volume 131
Bulletin of Experimental Biology and Medicine : Volume 130
Bulletin of Experimental Biology and Medicine : Volume 129
Bulletin of Experimental Biology and Medicine : Volume 128
Bulletin of Experimental Biology and Medicine : Volume 127
Bulletin of Experimental Biology and Medicine : Volume 126
Bulletin of Experimental Biology and Medicine : Volume 125
Bulletin of Experimental Biology and Medicine : Volume 124
Bulletin of Experimental Biology and Medicine : Volume 123

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Release-Activity: A Long Way from Phenomenon to New Drugs

Content Provider Springer Nature Link
Author Epstein, O. I.
Copyright Year 2012
Abstract Multiple dilutions of the original substance release its peculiar activity referred to as “releaseactivity”. Although this activity originates from the initial substance, it does not depend on its negligible concentration in extreme dilutions. Thus, the terms “dose”, “ultralow dose”, and “homeopathic dose”, do not correctly describe the release-active solutions, since the concept of dose implies the presence of some part of the original substance in a dilution with its intrinsic therapeutic potency. The data are reported on the molecular and cellular mechanisms of the mode of action of the release-active agents, some of which being introduced into clinical practice.
Starting Page 54
Ending Page 58
Page Count 5
File Format PDF
ISSN 00074888
Journal Bulletin of Experimental Biology and Medicine
Volume Number 154
Issue Number 1
e-ISSN 15738221
Language English
Publisher Springer US
Publisher Date 2012-11-23
Publisher Place Boston
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword release-activity release-active dilutions release-active preparations ultralow dose homeopathic dose Biomedicine general Internal Medicine Cell Biology Pathology Laboratory Medicine
Content Type Text
Resource Type Article
Subject Medicine Biochemistry, Genetics and Molecular Biology
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