NDLI: Gene regulation in Lactococcus lactis: the gap between predicted and characterized regulators

Content Provider	Springer Nature Link
Author	Guédon, Eric Jamet, Emmanuel Renault, Pierre
Copyright Year	2002
Abstract	The genome sequence of Lactococcus lactis IL1403 was previously determined with high quality, allowing a reliable determination of the potential ORFs present in the genome. It encodes 2310 proteins, and 138 of them were assigned as potential regulators, half of which being further classified by their similarity to known protein families. Among these regulators, most could have a direct role as transcriptional regulators, while the others may have less well defined functions in transcriptional regulation or more general functions, such as the GTP binding protein family. Current knowledge related to the regulators controlling gene expression in L. lactis will be confronted to data obtained in other bacteria. For example, comparison of the L. lactis regulators with those of B. subtilis reveals many orthologous regulators and also some clear differences in the type of regulator used in the two bacteria. Further comparison of the role and the effectors of orthologous regulators shows that direct transposition of a ‘heterologous model’ does not allow to build a reliable regulatory network in L. lactis. Moreover, many L. lactis regulators have functions that could not be proposed by transposition of the knowledge currently available in other bacteria. A considerable amount of work will be necessary to assess the function of L. lactis regulators and build a comprehensive model of the regulatory network. This would provide invaluable information on L. lactis biology and the way this bacterium interacts with the environment.
Starting Page	93
Ending Page	112
Page Count	20
File Format	PDF
ISSN	00036072
Journal	Antonie van Leeuwenhoek
Volume Number	82
Issue Number	1-4
e-ISSN	15729699
Language	English
Publisher	Kluwer Academic Publishers
Publisher Date	2002-01-01
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Medical Microbiology Food Science Plant Sciences Soil Science & Conservation
Content Type	Text
Resource Type	Article
Subject	Medicine Molecular Biology Microbiology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Genome plasticity in Lactococcus lactis

Respiration capacity and consequences in Lactococcus lactis

Transcriptome analysis and related databases of Lactococcus lactis

Low-redundancy sequencing of the entire Lactococcus lactis IL1403 genome

Experimental determination of control of glycolysis in Lactococcus lactis

In situ delivery of cytokines by genetically engineered Lactococcus lactis

Exopolysaccharides produced by Lactococcus lactis: from genetic engineering to improved rheological properties?

Steady state growth space study of Lactococcus lactis in D-stat cultures

Quasi steady state growth of Lactococcus lactis in glucose-limited acceleration stat (A-stat) cultures

Gene regulation in Lactococcus lactis: the gap between predicted and characterized regulators

Similar Documents

Genome plasticity in Lactococcus lactis

Respiration capacity and consequences in Lactococcus lactis

Transcriptome analysis and related databases of Lactococcus lactis

Low-redundancy sequencing of the entire Lactococcus lactis IL1403 genome

Experimental determination of control of glycolysis in Lactococcus lactis

In situ delivery of cytokines by genetically engineered Lactococcus lactis

Exopolysaccharides produced by Lactococcus lactis: from genetic engineering to improved rheological properties?

Steady state growth space study of Lactococcus lactis in D-stat cultures

Quasi steady state growth of Lactococcus lactis in glucose-limited acceleration stat (A-stat) cultures

Gene regulation in Lactococcus lactis: the gap between predicted and characterized regulators