NDLI: Measurement of Ultrasonic Attenuation in Diabetic Neuropathic Sciatic Nerves for Diagnostic and Therapeutic Applications

Content Provider	Springer Nature Link
Author	Chen, Gin Shin Lee, Yee Fun Cheng, Jung Sung
Copyright Year	2014
Abstract	Measurements of ultrasonic attenuation in the sciatic nerves of rats were performed to verify the feasibility of ultrasound diagnosis of peripheral neuropathy and to avoid damage to the nerves caused by overheating in pain management applications. A rat model of diabetic peripheral neuropathy was established. The proximal-segment and middle-segment sciatic nerves of control and neuropathic rats were dissected for the attenuation measurement. Two commercial ultrasound transducers and a self-developed experimental platform were used in the measurements. Using H&E staining and transmission electron (TE) microscopy, morphological analysis of the control and neuropathic nerves was performed to determine the relationship between attenuation and the histology of the nerves. The experimental results showed that the attenuation coefficients of the control, second-week, fourth-week, and eighth-week neuropathic nerves were −6.68 ± 0.50, −5.61 ± 0.34, −6.27 ± 0.40, and −7.10 ± 0.35 dB/cm at 2.68 MHz, respectively. The respective values at 7.50 MHz were −14.96 ± 0.79, −12.65 ± 0.28, −13.98 ± 1.07, and −16.00 ± 0.54 dB/cm. The changes in the attenuation coefficients were significantly different among the second-week, fourth-week, and eighth-week DN nerves. Additionally, the ultrasonic attenuation coefficient of the rat sciatic nerve was fourfold that of the cat brain and cow liver and twofold that of human muscle.
Starting Page	1749
Ending Page	1759
Page Count	11
File Format	PDF
ISSN	00906964
Journal	Annals of Biomedical Engineering
Volume Number	42
Issue Number	8
e-ISSN	15739686
Language	English
Publisher	Springer US
Publisher Date	2014-02-25
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Ultrasonic attenuation Transmission method Diabetic neuropathy Rat Sciatic nerve Biomedicine general Biomedical Engineering Biophysics and Biological Physics Mechanics Biochemistry
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Study on the use of quantitative ultrasound evaluation of diabetic neuropathy in the rat sciatic nerve

Image-Guided High-Intensity Focused Ultrasound for Conduction Block of Peripheral Nerves

In Vivo Contrast-Enhanced MR Imaging of Direct Infusion into Rat Peripheral Nerves

Stem Cells: Nuclear Reprogramming and Therapeutic Applications

Chronic Response of the Rat Sciatic Nerve to the Flat Interface Nerve Electrode

Computational Biomechanics for Patient-Specific Applications

Special Issues

March Editorial

Editorial Notes

Measurement of Ultrasonic Attenuation in Diabetic Neuropathic Sciatic Nerves for Diagnostic and Therapeutic Applications

Similar Documents

Study on the use of quantitative ultrasound evaluation of diabetic neuropathy in the rat sciatic nerve

Image-Guided High-Intensity Focused Ultrasound for Conduction Block of Peripheral Nerves

In Vivo Contrast-Enhanced MR Imaging of Direct Infusion into Rat Peripheral Nerves

Stem Cells: Nuclear Reprogramming and Therapeutic Applications

Chronic Response of the Rat Sciatic Nerve to the Flat Interface Nerve Electrode

Computational Biomechanics for Patient-Specific Applications

Special Issues

March Editorial

Editorial Notes

Measurement of Ultrasonic Attenuation in Diabetic Neuropathic Sciatic Nerves for Diagnostic and Therapeutic Applications